endothelial nitric oxide synthase

General Information (Source: NCBI Gene,UniProt)

Text mining Term endothelial nitric oxide synthase
UniProt ID Q8C5P3_MOUSE
Name Nitric oxide synthase
Gene Names Nos3
Taxonomy Mus musculus

General annotation

Function Produces nitric oxide (NO) (By similarity).
Subcellular location

Gene Ontology

GO:0031663 lipopolysaccharide-mediated signaling pathway BP
GO:0051926 negative regulation of calcium ion transport BP
GO:0043267 negative regulation of potassium ion transport BP
GO:0004517 nitric-oxide synthase activity MF
GO:0010181 FMN binding MF
GO:0050661 NADP binding MF
GO:0001525 angiogenesis BP
GO:0020037 heme binding MF
GO:0001701 in utero embryonic development BP
GO:0051346 negative regulation of hydrolase activity BP
GO:0005737 cytoplasm CC
GO:0006809 nitric oxide biosynthetic process BP
GO:0050660 flavin adenine dinucleotide binding MF
GO:0002028 regulation of sodium ion transport BP
GO:0005516 calmodulin binding MF
GO:0030324 lung development BP
GO:0001542 ovulation from ovarian follicle BP
GO:0005634 nucleus CC

Sequence

>gi|161086988|ref|NP_032739.3| nitric oxide synthase, endothelial [Mus musculus]
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPAPPSPTRPAPDHSPPLTRPPDGPRFPRV
KNWEVGSITYDTLSAQAQQDGPCTSRRCLGSLVFPRKLQSRPTQGPSPTEQLLGQARDFINQYYNSIKRS
GSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRTAQEMFTYI
CNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLIRYAGYRQQDGSVRGDPANVEITELCIQHGWTP
GNGRFDVLPLLLQAPDEPPELFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAA
PFSGWYMSSEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGAGIT
RKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSL
EHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRK
ESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQA
AFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQS
SKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYEEWKWFSCPTL
LEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTIAVLAYRTQDGLGPLHYGVCSTWMS
QLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPFRGFWQDRLHDIEIKGLQPAPMTLVFGCRCS
QLDHLYRDEVLDAQQRGVFGQVLTAFSRDPGSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMAT
SVLQTVQRILATEGGMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPW
SFDPPGPEIPGS

Options for BLAST

Database:

Set subsequence:(optional):
From: To:

Optional parameters:
Expect:
Descriptions:

Database Cross Reference

Ensembl Gene
UniGene Mm.258415
PDB
RefSeq NP_032739.3
Pfam PF00258
PF02898
PF00175
PF00667