| Text mining Term | proton pump |
|---|---|
| UniProt ID | AT12A_MOUSE |
| Name |
Potassium-transporting ATPase alpha chain 2 Proton pump Non-gastric H(+)/K(+) ATPase subunit alpha |
| Gene Names |
Atp12a
Synonyms:Atp1al1 |
| Taxonomy | Mus musculus |
| Function |
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues. |
|---|---|
| Subcellular location |
Membrane; Multi-pass membrane protein. |
| GO:0008900 | hydrogen | MF |
| GO:0005524 | ATP binding | MF |
| GO:0016021 | integral to membrane | CC |
| GO:0046872 | metal ion binding | MF |
| GO:0055075 | potassium ion homeostasis | BP |
| GO:0006754 | ATP biosynthetic process | BP |
>gi|157168326|ref|NP_619593.2| potassium-transporting ATPase alpha chain 2 [Mus musculus] MRRKTEIYSVELNGTKDVELADQKDDKKFKGGKNKDSEPNKSQEEELKKELDLDDHRLSNTDLEQKYGTN IIQGLSSIRAAELLARDGPNALTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAYVIQYVSSTASLDN VYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKIIPAEQLVVGDVVEIKGGDQI PADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGR IASLASGVGSEKTPIAIEIEHFVHIVAAVAVSVGVIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLAT VTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQTKQ AFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRVVVGDASETALLKFSEVILGDVMDIRKRNHKVAE IPFNSTNKFQLSIHETEDPNDKRFLMVMKGAPERILEKCSTIMINGQEQPLDKSSADAFHTAYMELGGLG ERVLGFCHLYLPADKFPQSYTFDVDSINFPTSNLCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGD HPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLINYQEIV FARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIV TGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAES DIMNRKPRHKKKDRLVNKQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVSWETDDINDLE DSYGQEWTRYQRKYLEWTGSTAFFVAIMVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIISQIIVALVL SYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY |
| Ensembl Gene |
ENSMUST00000007340 |
|---|---|
| UniGene |
Mm.273271 |
| PDB | |
| RefSeq |
NP_619593.2 |
| Pfam |
PF00690 PF00689 PF00702 PF00122 |