ER beta

General Information (Source: NCBI Gene,UniProt)

Text mining Term ER beta
UniProt ID B2RUC6_MOUSE
Name Estrogen receptor 2 (Beta)
Uncharacterized protein
Gene Names Esr2
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0006351 transcription, DNA-dependent BP
GO:0060766 negative regulation of androgen receptor signaling pathway BP
GO:0043565 sequence-specific DNA binding MF
GO:0060065 uterus development BP
GO:0030520 estrogen receptor signaling pathway BP
GO:0043065 positive regulation of apoptotic process BP
GO:0060743 epithelial cell maturation involved in prostate gland development BP
GO:0005634 nucleus CC
GO:0007420 brain development BP
GO:0001764 neuron migration BP
GO:0001541 ovarian follicle development BP
GO:0050680 negative regulation of epithelial cell proliferation BP
GO:0008270 zinc ion binding MF
GO:0003700 sequence-specific DNA binding transcription factor activity MF
GO:0060740 prostate gland epithelium morphogenesis BP
GO:0060068 vagina development BP
GO:0003707 steroid hormone receptor activity MF
GO:0005496 steroid binding MF

Sequence

>gi|46877094|ref|NP_034287.3| estrogen receptor beta isoform 2 [Mus musculus]
MSICASSHKDFSQLRPTQDMEIKNSPSSLTSPASYNCSQSILPLEHGPIYIPSSYVESRHEYSAMTFYSP
AVMNYSVPSSTGNLEGGPVRQTASPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVNR
ETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQC
TIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSASEQVHCLNKAKRTSGHTPRVKELLLN
SLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLL
ESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVK
AMILLNSSMYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNK
GMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECCSTEDSKSKEGSQNLQSQ

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000110421
ENSMUST00000076634
UniGene Mm.2561
PDB
RefSeq NP_034287.3
Pfam PF00104
PF00105
PF12497