Text mining Term | pg m |
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UniProt ID | CSPG2_RAT |
Name |
PG-M Chondroitin sulfate proteoglycan core protein 2 Glial hyaluronate-binding protein Versican core protein Large fibroblast proteoglycan GHAP Chondroitin sulfate proteoglycan 2 |
Gene Names |
Vcan
Synonyms:Cspg2 |
Taxonomy | Rattus norvegicus |
Function |
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. |
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Subcellular location |
Secreted, extracellular space, extracellular matrix. |
GO:0005509 | calcium ion binding | MF |
GO:0005529 | sugar binding | MF |
GO:0030169 | low-density lipoprotein particle binding | MF |
GO:0005540 | hyaluronic acid binding | MF |
GO:0031103 | axon regeneration | BP |
GO:0007155 | cell adhesion | BP |
GO:0005578 | proteinaceous extracellular matrix | CC |
>gi|281604090|ref|NP_001164029.1| versican core protein isoform 1 precursor [Rattus norvegicus] MLINMNGILWMCSTLLLTHALHKAKMEENPPVKGSLSGKVILPCHFSTLPTLPPDYNTSEFLRIKWSKIE VDKNGKDIKETTVLVAQDGNIKIGQDYKGRVSVPTHPDDVGDASLTMVKLRASDAGVYRCDVMYGIEDTQ NTMSLAVDGVVFHYRAATSRYTLNFESAQQACLDIGAVIATPEQLFAAYEDGFEQCDAGWLSDQTVRYPI RAPREGCYGDMMGKEGVRTYGFRSPQETYDVYCYVDHLDGDVFHITAPSKFTFEEAEAECANRDARLATV GELHAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTCFPLPDSRFDAYCFKPKQ NISEATTIETNTLAETASPSLSKEPHMVPERATPVIPLVTELPIFTTHFPPAGNIVNSEQKSVIYSQAIT DRVATESPTAAGSPINSWDADDYLPSGSGPLGKPDISEIKEEGLQSTTVTSQHATASHHGITEDTQTHES VTQIEQIEVGPLVTSMEITNHISFKEFLETKTPLESTEVTLEQHQTDMPTVITSPELATTSHYGVTLRED DREDIALTVRSGQSTRVFSQIPEVITVSKTSEDTTYSQLGDLEFVSTATITMLGTDGSLTDEGKEPQTDD KTAEDEFGQSQPTIPFPSQHLTEVESLPYSGDTISVERISTVSYPSLQTDVTQGRERTEVPRPGLKKDPY AVDEIQEKITKDPFIGTIEEGFSGMSLSTSSSETSAERTESVSPALTIEKLTVKPAVASDVDEMTILTRL ETDVPTSDEDVTSAHLTHSTLNVEVVTVLKWPGNEDNSTSKPLPPTERAGFTKSPPVSLSTVGIVGKDKE TPSFTDGGDEYTLSLDGTPKPLEKFSEEDLTSGEFAVTIPTSISIDSAEKSTLGEPTTGDRVLSTTSTKD LVINATVEGSALDEDMDASKPLFTATPFVHTSDVEESAFVNYSSTQQPTTYVDISHTSPLSIIPKTEWSV SETSVPLEDEVLGKSDQDTLEQTHLEATMSPEALSTIEVTQGETQEEPQTPGIPFPALSSTAVMTKETTA FEEEGEGSTYTLSEDRLMTDSEIVPSLETTPVGTSYPGGAMTQQEVEMDTMVTQMSSIRPTVVLSTEPEV SYEAEGSSPMEFASTLKPFGTQVTQLVEETTEEGKKTPLDYTDLGSGLFEQPRVTELPDFSMTPSDISVF TAIDSLHRTTPLRPPSPFTEEPHIFEKEPSEKTTGDIILPRESVTQHPLTTLMDIIAKKTESDIDHEYHM TSKPPVMQPTRPSVVERKTTSKPQELSTSPPPAGTKFHPDINVYIIEVRENKTGRMSDMVVNGHPIDSES KEEEPCSEETDPLHDLFAEILPELPDSFEIDIYHSEEDEDGEEDCVNATDVTTTPSVQYITGKPHVTTVP KNPEAAEARRGLYESVAPSQNFSNTSATDTHQFIPAETELSTTMQFTKSKEATELLEITWKPETYPETPE HFSSGEPDVFPTLPSHDGKTTKWSEFITESNPNTENPEHKQPKPIPLFPEEFSGEGAIDQASQQTIFSRA TEVALGKETDQSPTISTSSIRSGSVSVHALEEDPIALTGISQTDESMSTVESWVEMTPSQTVEFSGSSSA PTIEGSGEVEEYTNKIFNTVTDLPQREPTDTLIPLDMSNIMITDHHIYTPATTAPLDSQLPSTDARPTQF GIQTTTSEWVSSTSFEGRKTEEDKERDTNAAHTGEVQPATERSDRLLLTSELESSNVAASSPLDTWEGFV PETTSTVSEKEMANTTPVFTETSDVANLETQSFEHSSSSQPRVQEELTTLSGKPPLIFMDLGSGDASTDM EFITASSFTLDLESDTKVKKELPSTLSPSVETSSSSEPIGLAPSTVLDIEIVEVMNQTSKKTLISELSGK PTSQAEVRDLYPGLGEDFSGDSSEYPTVSSTTMKEETVGMGGSENERVKDTQTLSSIPPTSDNINPVPDS KGFGSTVASTTAFPWEEFMTSAEGSGEELSSVRSSVSLVLPLGVDILPTTESPYFDQEFEEAAAVTEAGK QSALPIAVSGNTVDLTENRDIEVNSTMSVDLPQTMEPAKLWSKPEVNPEKQEIGSETVTQDKAQGQKSFE SLHSSLAPEQTTLESQSLIETEVQTSYYSMLTTMKTYNTNEEVEEEGTSIAHMSTPGPGIKGLESYPTHP EATGKSYSFSASALVTESGPARSVVMDSSTQEEESIKLFQKDMILTHKESNSDLSFSGLGSGEALPPLPT TSVSLTDMGKINSTLYPETSHMESLGTSILGDNHERMKNVSNEVRTLISETGSISQDSTEAPNTTLSDTR TEESTTSPLPFMKLMDTEHSPKQTLRWEEEIQTHRPQTMTGQMTNDNSSVSEAEAAATSAPAFLPETYSV EMTKAFATSPSQTSDLFDANSGEGSGEVDGLDLVYTSRTTQASSQGDSMFASHGFIEKHPEVSRTETGAT DGSPTASAMFLHQSEYNESSLYPTSTLPSTVTYESPSEGIADGLQDHIRFEVSTLKPSRRKATESVIIDL DKEDSKDLGLAITESAIVEILPELTSDRNIIIDIDHTKPVYEYIPGIQTDLDSDIPLGSHGSSEESLEVQ EKYEATINLSPTEEAFDGSGDALPAGHTQAIYNESVTPSDGKQPEDISFSFATGIPVSSTETELNTFFPT VSTLHIPSKLTTASPEIDKPNIEAISLDDIFESSTLSDGQAIADQSEVISTLGHLEKTQEEYEEKKYGGP SFQPEFFSGVGEVFTDAPAYVSIGRTYSVAQPLTEFPNVVGQSDSTHYTEATSAVSSVTELSPQTPSSPS PVYIDSGVSEFTEVPHKSAQPAPTAASSQKLIEGSFKKVRANIEATIKSLGENDHGTESPSMSPSPALDI SEDDSKPKLLEDLETSPTKTETSQDSPNKANDQIPGKTAGILAGIKTTESGPVVTAADDMELGDATQRPH SASAPAAFRVETSMVPQPIPQEPERPTFPSLEINHETHTSLFEESILATSEKQVSQRILDYSNQATVSTL DLNTEHSIPPFSILDNSNETAFLIGISEETVEGTAVYLPGPDLCKTNPCLNGGTCYPTETSYVCTCAPGY SGDQCELDFDECHSNPCRNGATCVDGLNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRT WDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSALQYENWRPNQPDSFF SAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGF IQRHLPTIRCLGNGRWAMPKITCMNPSAYQRTYSKKYLKNSSSVKDNSINTSKHEHRWSRRWQETRR |
Ensembl Gene | |
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UniGene |
Rn.35666 |
PDB | |
RefSeq |
NP_001164030.1 NP_001164031.1 NP_001164029.1 |
Pfam |
PF07686 PF00193 PF00008 PF00084 PF00059 |