Keratinocyte growth factor

General Information (Source: NCBI Gene,UniProt)

Text mining Term Keratinocyte growth factor
UniProt ID FGF7_RAT
Name Keratinocyte growth factor
KGF
HBGF-7
Fibroblast growth factor 7
FGF-7
Heparin-binding growth factor 7
Gene Names Fgf7
Taxonomy Rattus norvegicus

General annotation

Function Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
Subcellular location

Gene Ontology

GO:0008083 growth factor activity MF
GO:0005111 type 2 fibroblast growth factor receptor binding MF
GO:0006656 phosphatidylcholine biosynthetic process BP
GO:0042060 wound healing BP
GO:0008201 heparin binding MF
GO:0043129 surfactant homeostasis BP
GO:0001541 ovarian follicle development BP
GO:0051781 positive regulation of cell division BP
GO:0005615 extracellular space CC

Sequence

>gi|11559943|ref|NP_071518.1| keratinocyte growth factor precursor [Rattus norvegicus]
MRKWILTRILPTPLYRPCFHLVCLVGTISLACNDMSPEQTATSVNCSSPERHTRSYDYMEGGDIRVRRLF
CRTQWYLRIDKRGKVKGTQEMRNSYNIMEIMTVAVGIVAIKGVESEYYLAMNKQGELYAKKECNEDCNFK
ELILENHYNTSASAKWTHSGGEMFVALNQKGLPVKGKKTKKEQKTAHFLPMAIT

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.98842
PDB 1QQL
1QQK
RefSeq NP_071518.1
Pfam PF00167