cholinesterase

General Information (Source: NCBI Gene,UniProt)

Text mining Term cholinesterase
UniProt ID Q9JKC1_RAT
Name Butyrylcholinesterase
Gene Names Bche
Taxonomy Rattus norvegicus

General annotation

Function
Subcellular location

Gene Ontology

GO:0016020 membrane CC
GO:0005788 endoplasmic reticulum lumen CC
GO:0042493 response to drug BP
GO:0051384 response to glucocorticoid stimulus BP
GO:0043279 response to alkaloid BP
GO:0051593 response to folic acid BP
GO:0033265 choline binding MF
GO:0005615 extracellular space CC
GO:0005624 membrane fraction CC
GO:0007271 synaptic transmission, cholinergic BP
GO:0003990 acetylcholinesterase activity MF
GO:0007612 learning BP
GO:0050805 negative regulation of synaptic transmission BP
GO:0019695 choline metabolic process BP
GO:0004091 carboxylesterase activity MF

Sequence

>gi|12621110|ref|NP_075231.1| cholinesterase precursor [Rattus norvegicus]
MVTEIHFLLWILLLCMLFGKSHTEEDVIITTKTGRVRGLSMPILGGTVTAFLGIPYAQPPLGSLRFKKPQ
PLNKWPDVYNATKYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVPKPKNATVMVWVYGGG
FQTGTSSLPVYDGKFLTRVERVIVVSMNYRVGALGFLAFPGNSEAPGNMGLFDQQLALQWIQRNIAAFGG
NPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFIGCSKENE
KEIITCLRSKDPQEILLNEKLVLPSDSIRSINFGPTVDGDFLTDMPHTLLQLGKVKTAQILVGVNKDEGT
AFLVYGAPGFSKDNDSLITRREFQEGLNMYFPGVSSLGKEAILFYYVDWLGDQTPEVYREAFDDIIGDYN
IICPALEFTKKFAELEINAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEIFSRSI
MKTWANFAKYGHPNGTQGNSTVWPVFTSTEQKYLTLNTEKSKINSKLRAPQCQFWRLFFPKVLEITGDID
EREQEWKAGFHRWSNYMMDWKNQFNDYTSKKETCTDL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.48791
PDB
RefSeq NP_075231.1
Pfam PF00135
PF08674