fibroblast growth factor receptor

General Information (Source: NCBI Gene,UniProt)

Text mining Term	fibroblast growth factor receptor
UniProt ID	FGFR1_DROME
Name	Tyrosine kinase 1 Fibroblast growth factor receptor homolog 1 Protein heartless dTk1 DmHD-38
Gene Names	htl
Taxonomy	Drosophila melanogaster

General annotation

Function	May be required for patterning of muscle precursor cells. May be essential for generation of mesodermal and endodermal layers, invaginations of various types of cells and CNS formation.
Subcellular location	Membrane; Single-pass type I membrane protein.

Gene Ontology

GO:0008347	glial cell migration	BP
GO:0048542	lymph gland development	BP
GO:0007493	endodermal cell fate determination	BP
GO:0008284	positive regulation of cell proliferation	BP
GO:0010002	cardioblast differentiation	BP
GO:0008078	mesodermal cell migration	BP
GO:0016021	integral to membrane	CC
GO:0005515	protein binding	MF
GO:0048747	muscle fiber development	BP
GO:0010001	glial cell differentiation	BP
GO:0007523	larval visceral muscle development	BP
GO:0007500	mesodermal cell fate determination	BP
GO:0007419	ventral cord development	BP
GO:0007280	pole cell migration	BP
GO:0005524	ATP binding	MF
GO:0005007	fibroblast growth factor-activated receptor activity	MF
GO:0007506	gonadal mesoderm development	BP
GO:0007513	pericardial cell differentiation	BP
GO:0007525	somatic muscle development	BP
GO:0007431	salivary gland development	BP
GO:0008360	regulation of cell shape	BP

Sequence

>gi|285756|dbj|BAA03617.1| fibroblast growth factor receptor [Drosophila melanogaster]
MAAAWSWRASHSTITMTSGSVVVLFLLLTIWQPAVQVEGRRQMANSQEMIKDHLGARSQNKTPAITNNAN
QSSTSSADLDDGAADDDDNKADLPVNVSSKPYWRNPKKMSFLQTRPSGSLLTLNCHALGNPEPNITWYRN
GTVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTL
VVNSTGSSHCKYLSDLTSKKAWIFVPVHGMTNCSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQ
SNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVH
QWTKKVIIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLG
ATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVI
VEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAA
RNVLVSDDYVQKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTY
GQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYL
DVDIANLDTPPSTSDEEEDETDNLQKWCNY

Database Cross Reference

Ensembl Gene
UniGene	Dm.7690
PDB
RefSeq	NP_732287.1 NP_732286.1 NP_524394.2
Pfam	PF07714 PF07679

PTID

fibroblast growth factor receptor

General Information (Source: NCBI Gene,UniProt)

General annotation

Gene Ontology

Sequence

Options for BLAST

Database:

Set subsequence:(optional):

Optional parameters:

Database Cross Reference