glutathione reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term glutathione reductase
UniProt ID GSHR_SCHPO
Name GRase
GR
Glutathione reductase
Gene Names pgr1
Taxonomy Schizosaccharomyces pombe 972h-

General annotation

Function Maintains high levels of reduced glutathione in the cytosol.
Subcellular location Cytoplasm (By similarity).

Gene Ontology

GO:0005739 mitochondrion CC
GO:0050660 flavin adenine dinucleotide binding MF
GO:0034599 cellular response to oxidative stress BP
GO:0006749 glutathione metabolic process BP
GO:0004362 glutathione-disulfide reductase activity MF
GO:0045454 cell redox homeostasis BP
GO:0050661 NADP binding MF

Sequence

>gi|19112381|ref|NP_595589.1| glutathione reductase [Schizosaccharomyces pombe 972h-]
MAPISKVFDYLVIGGGSGGLASARRAAKHGAKVALIEASGRLGGTCVNYGCVPKKIMWNIADLVAKMKTA
KQNGFPNSQLGSFDWGMIKRKRDAYIGRLNGIYERNVNKDGVAYISGHASFVSPTEVAVDMNDGSGTQVF
SAKYILIAVGGHPIWPSHIPGAEYGIDSDGFFELESQPKRVAIVGAGYIAVELAGVFAALGTETHMFIRQ
SKFLRKFDPIISDGIMDHFQHIGINVHTNSLEFKKVEKLPSGELCIHQQDGSTFNVDTLLWAIGRAPKIQ
GLRLEKAGVKTLPNGIIIADTYQRTNVPTVLSLGDVCGKLELTPVAIAAGRRLSDRLFGGIKDAHLDYEE
VPSVVFAHPEAGTIGLTEQEAIDKYGESQIKVYNTKFNGLNYSMVEQEDKVPTTYKLVCAGPLQKVVGLH
LVGDFSAEILQGFGVAIKMGATKSDFDSCVAIHPTSAEELVTLV

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq NP_595589.1
Pfam PF07992
PF02852
PF00070