novel proteins

General Information (Source: NCBI Gene,UniProt)

Text mining Term novel proteins
UniProt ID MELT_DROME
Name Protein melted
Gene Names melt
Taxonomy Drosophila melanogaster

General annotation

Function Participates in fat metabolism regulation by recruiting FOXO and the TSC1-TSC2 complex to the cell membrane, which positively regulates TOR activity and negatively regulates the expression of FOXO target genes. Involved in R8 photoreceptor subtype specification. During early embryonic development, may be required for ectodermal patterning.
Subcellular location Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Gene Ontology

GO:0030730 sequestering of triglyceride BP
GO:0010314 phosphatidylinositol-5-phosphate binding MF
GO:0045464 R8 cell fate specification BP
GO:0008286 insulin receptor signaling pathway BP
GO:0005515 protein binding MF
GO:0005886 plasma membrane CC
GO:0007422 peripheral nervous system development BP
GO:0007398 ectoderm development BP
GO:0006629 lipid metabolic process BP

Sequence

>gi|353526257|sp|Q9VS24.2|MELT_DROME RecName: Full=Protein melted
MHELFNKVLAKRDLSRAGDLFSVPDADIVDDITEVLSEISPIISHADYVKNNNDQSVVEICVTRVLSCIR
ETKTAERYCAALVDLLRTCLLWNLQPSGTTKEEPPHAKIAADIISSIFLNYDKKELMKIALPVAVQFLPK
GNRELSRNLASYLSLAAIDHAGLLSPHTESVMESILSGNYGLLRVLSQVYEVAPEAVTPHAPLLMPLLPQ
CDPQERMAVFQLYLLIVQKSPEVLESCVPQLCGSLLDSDTSSITMQILLKLSQHSPSLLVDHFEQLRLAA
KTNPGTIPLCAQIMTTAGIGSKETAQQALDFVLEHLPTQALLQQEATRLCSAYPVLFTDKVLACVRQKNA
ALSSQQDVGNGLANKTSGGVTIVSLNSSSPSPPLKPVPVGAPAINTTIVQPASVVSATPTPPPSSASAPI
ASSTPVSAATPTPQHAGYTRRVKLGDSRSTGRLHPASNTHRSVTRLNVASGSVGGLHKSMTRLSNSQINQ
QPGGSSNGNVVVQSGATPKTPTGLSNPPVTPVPPLSNNVVITGHNRHGIPVTSGGVTVTTSPSKVRPHSQ
GPSTLLNSSTVLMKYSTDALNQSVGSISIPQSAAVATLPSTQTQNAVSVHHASPALPQSASNGHAKSVMK
LPVNGNSEVIVSGPTTNVAPRRSDNTSRTLLNANSVMDQRMSTFEPYQIMRDPVQQFCEKNFNSIKSYMD
EVSQHLPPPTRCSIEVSNEFAERRTKKVAKLHFACQIRGPHCLYSKTCFTMRTRNPKTWIHMMFLDFQVR
HFVKEKCVLSTRESGISNLKNIWQILKCENRSFTELVTSQFPQVKDREILVNELRHSGFLDVFEVSKTDK
SNPNCNELEYQWGCFLCNHPDKAVGFLNGSNQPMIEGQLKEKKGKWRLFRRWRTRYFTLSGAHLSCKGSS
GGESIDVNQIRSVKVSRGARNIPKAFEIFTADQTLILKPKDGKNAEEWVQCLSIVVAHSQARDNPTAKTN
SLPARSIGSSKPSF

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dm.9528
PDB
RefSeq NP_001014572.1
NP_523953.2
Pfam PF00169