NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID O04434_PEA
Name NADPH--cytochrome P450 reductase
Gene Names PSC450R1
Taxonomy Pisum sativum

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0005506 iron ion binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF
GO:0010181 FMN binding MF

Sequence

>gi|6503253|gb|AAC09468.2| putative NADPH-cytochrome P450 reductase [Pisum sativum]
MQDSSTMKFSPLDLMTAIIKGKFNPSNDSSQAPASIIFENREFVMILTTSIAVLIGCVVVLIWRRSNSNK
SKQIEVPKLVIKKLPELDVDDGKKKVTVFFGTQTGTAEGFAKAIAEEAKARYEKAKFRVVDMDDYAADDD
EYLEKLKRETMALFFLATYGDGEPTDNAARFYKWFTEEYEGEEDSFKNLSYGVFGLGNRQYEHFNKVAKV
VDDKLLEQGGKRLVPVGLGDDDQCIEDDFTAWKEELWPALDQLLRDEDDTPVATPYTAAVSEYRVVIHDP
LDATVDEKKRHNVNGHAVVDAQHPVRANVAVRRELHTPASDRSCTHLEFDISGTGVVYETGDHVGVYCEN
LSDTVEEAERILGLSPDTYLSIHTDDEEGKPLGGSSLPPPFPPCTLRTALTKYADLLSSPKKSALVALAA
HASDPSEADRLRHLASPAGKDEYAEWVISSQRSLLEVMAEFSSAKPPIGVFFAAVAPRLQPRYYSISSSP
RMAPSRIHVTCALVHDKMPTGRIHKGVCSTWMKNSVPLEKNQDCSWAPIFVRQSNFRLPADNKVPVIMIG
PGTGLAPFRGFLQERLALKEDGAELGPSVLFFGCRNRQVDYIYEDELNHFVNGGALSELIVAFSRDGPTK
EYVQHKMMEKASDIWNMISQGAYVYVCGDAKGMARDVHRTLHTILQEQGSLDSSKTESMVKNLQMTGRYL
RDVW

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00175
PF00258
PF00667