NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID D6X2B1_TRICA
Name NADPH--cytochrome P450 reductase
Gene Names
Taxonomy Tribolium castaneum

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0010181 FMN binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF
GO:0005506 iron ion binding MF

Sequence

>gi|270013791|gb|EFA10239.1| hypothetical protein TcasGA2_TC012437 [Tribolium castaneum]
MDEAEASLGTQQIPEASESLFSTIDIILLTLLIGGVAWWFLNKQKKKDVAATARSYSIQPTSMTLQTSSD
NSFIKKLKSSGRSLVVFYGSQTGTGEEFAGRLAKEGVRYRLKGMVADPEECDMEELVNLKSIPNSLAVFC
LATYGEGDPTDNAMEFYEWLQNGDADLSGLNYAVFGLGNKTYEHYNQVAIYVDKRLEELGATRVFDLGLG
DDDANIEDDFITWKDKFWPAVCEHFGIESTGEDVSMRQYRLQEFKDEVPEKLYTGEMARLHSLKNQRPPF
DAKNPFLAKILVNRELHKGNDRSCMHIEFDIEGSKMRYDAGDHVAVYPINDSDLVEKIGKLTNTDLDTIF
TLINTDEESSKKHPFPCPTTYRTALTHYLDITMNPRTHVLKELSEYCTDPAEKEKLKTMASTSPEGKALY
QQWVNEDNRNIVHILEDMPSCKPKLDHLCELLPRLQPRYYSISSSPKLYPNTVHITAVVVEYKTPTGRHN
KGVCTTWLALKKPAPGQEPPTAPIFIRKSQFRLPTKTQTPIIMIGPGTGLAPFRGFIQERHQAKEEDKAV
GETVLYFGCRKKAEDFIYEEELLNYEKSGLLTLHLAFSRDQAHKVYVSHLLEKNREEVWRIIGENNGHLY
ICGDAKSMAPEVRNIVMKIIQDKGQMTEQQASAYLKKMETQKRYSADVWS

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Tca.10219
PDB
RefSeq XP_971174.1
Pfam PF00258
PF00175
PF00667