NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID E0A3A7_HELAM
Name NADPH--cytochrome P450 reductase
Gene Names CPR
Taxonomy Helicoverpa armigera

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0003958 NADPH-hemoprotein reductase activity MF
GO:0010181 FMN binding MF
GO:0005506 iron ion binding MF

Sequence

>gi|304569603|gb|ADM45306.1| NADPH cytochrome P450 reductase [Helicoverpa armigera]
MSDSAQDVLKDAATGAAAAAAAGGSLFSTFDIIVLVILLGGTIWWLYNSKKENKKDEILLSKYSIQAAGS
IQVTENSFINKLKSSGRSLVVFYGSQTGTGEEFAGRLAKEGIRYKMKGMVADPEECDMEELMKLQDIPNS
LAVFCMATYGEGDPTDNSMEFYEWLKNGEPDLTGLNYAVFGLGNKTYEHYNAVAIYLDKRLEELGATRVY
ELGLGDDDANIEDDFITWKDKFWPAVCEKFNIESTGEEELIRQFRLVTHAPGDIQPNNVFTGEIARLHSL
QVQRPPYDAKNPFLAQITVNRELHKGGDRSCIHVELDISDSKMRYEAGDHVAVYPINDTNLVERLGQLTG
ANLDEIFSLINTDQESSKKHPFPCPTSYRTALSHYVEITALPRTHILRELVEYCSDEEDKKKLMLMATNS
QEGKALYQSFIVDACRNIVHILEDIPSCKPPLDHLCELLPRLQPRYYSISSSPKMYPETVHITAVIVKYK
TPTGRVNKGVTTTWLAENKPEPGKPLPRVPVYIRKSQFRLPLQTQTPIIMVGPGTGLAPFRGFLQERAFA
RANGKEVGESVLYFGCRHRDQDYIYQDELEKYEQNGDVKLNLAFSRDQKEKVYVTHLLEKDMDLLWDVIG
NRNGHFYICGDAKNMAVDVRNIVLKAIQEKGGRTESEAVQFIKKLESMKKYSADVWS

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00258
PF00667
PF00175