NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID B4Q4L3_DROSI
Name NADPH--cytochrome P450 reductase
Gene Names GD23403
Taxonomy Drosophila simulans

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0005506 iron ion binding MF
GO:0010181 FMN binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF

Sequence

>gi|194190364|gb|EDX03940.1| GD23403 [Drosophila simulans]
MASEQTIDGAATIPSGGGDEPFLGLLDVALLAVLIGGAAFYFLRSRKKEEEPTRSYSIQPTTVCTTSASD
NSFIKKLKASGRSLVVFYGSQTGTGEEFAGRLAKEGIRYRLKGMVADPEECDMEELLQLKDIDNSLAVFC
LATYGEGDPTDNAMEFYEWITSGDVDLTGLNYAVFGLGNKTGGHYNKVAIYVDKRLEELGANRVFEVGVG
DDDANIEDDFITWKDRFWPAVCDHFGIEGGGEEVLIRQYRLLEQPEVQPDRIYTGEIARLHSIQNQRPPF
DAKNPFLAPIKVNRELHKGGGRSCMHIELSIDGSKMRYDAGDHVAMFPVNDKSLVEKLGQLCNADLDTVF
SLINTDTDSSKKHPFPCPTTYRTALTHYLEITAIPRTHILKELAEYCTDEKEKELLRSMASISPEGKEKY
QSWIQDACRNIVHILEDIKSCRPPIDHVCELLPRLQPRYYSISSSAKLHPTDVHVTAVLVEYKTPTGRIN
KGVATTYLKNKQPQGSEEVKVPVFIRKSQFRLPTKPETPIIMVGPGTGLAPFRGFIQERQFLRDEGKTVG
ESILYFGCRKRSEDYIYESELEEWVKKGTLNLKAAFSRDQGKKVYVQHLLEQDADLIWNVIGENKGHFYI
CGDAKNMAVDVRNILVKILSTKGNMSEADAVQYIKKMEAQKRYSADVWS

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dsi.4219
PDB
RefSeq XP_002078355.1
Pfam PF00258
PF00667
PF00175