succinate dehydrogenase (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term succinate dehydrogenase (protein family or complex)
UniProt ID SDF2B_DROSI
Name Succinate dehydrogenase subunit 5-B, mitochondrial
SDH assembly factor 2-B
Succinate dehydrogenase assembly factor 2-B, mitochondrial
Gene Names
Taxonomy Drosophila simulans

General annotation

Function Required for insertion of FAD cofactor into Scs-fp, the catalytic subunit of succinate dehydrogenase (SDH). SDH is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). In is unclear whether it participates in the chemistry of FAD attachment (enzymatic function) or acts as a chaperone that maintains Scs-fp in a conformation that is susceptible to autocatalytic FAD attachment (By similarity).
Subcellular location Mitochondrion (By similarity).

Gene Ontology

GO:0006121 mitochondrial electron transport, succinate to ubiquinone BP
GO:0018293 protein-FAD linkage BP
GO:0005739 mitochondrion CC

Sequence

>gi|257096764|sp|B4QID8.1|SDF2B_DROSI RecName: Full=Succinate dehydrogenase assembly factor 2-B, mitochondrial; Short=SDH assembly factor 2-B; AltName: Full=Succinate dehydrogenase subunit 5-B, mitochondrial; Flags: Precursor
MLRQFIVSTVGRRLQLPMMAQSRLASNLDKTEYTTPGEIVDYDDPPHLPVPEYPVRPDEPLEIRKQRLLY
QSRKRGMLENDLLLSTFVAKHLKDFNAEQTAEYDQLINGVSNDWDIFYWATDTKPTPPQFDTEIMRLLKE
HVKNHEKVQRIRQPDL

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_002080913.1
Pfam PF03937