| Text mining Term | protein kinase C (protein family or complex) |
|---|---|
| UniProt ID | KPC2_APLCA |
| Name |
Calcium-independent protein kinase C APL II |
| Gene Names |
PRKC2
|
| Taxonomy | Aplysia californica |
| Function |
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity). |
|---|---|
| Subcellular location |
Membrane; Peripheral membrane protein. |
| GO:0016020 | membrane | CC |
| GO:0004697 | protein kinase C activity | MF |
| GO:0046872 | metal ion binding | MF |
| GO:0035556 | intracellular signal transduction | BP |
| GO:0005524 | ATP binding | MF |
>gi|155792|gb|AAA27771.1| protein kinase C [Aplysia californica] MSRRAKMVFNGSVKIKVCEAVDLKPTDFSLRLQKGSTKEKASQMIEPYVNIDVDEVYIAKTTTKPKSVKP QWVWNEDFTSEVHNGQNVNLTVFHDAAIPPDEFVANCTIPFDDVKGKSDFWIDLEPNGKLHVVIELCGSA TEAAESTPKEKVFKEKEGMLNRRRGAMRRRVHQVNGHKFMAMFFRQPTFCSLCRDFIWGLGKQGYQCQVC TCVVHKRCHQHIVTKCPGSRDVANDEVTGKRFNINVPHRFNVHNYRRPTFCDHCGSLLYGLVRQGLQCDV CKMNIHKRCQKNVANNCGTNTRDMAQILQEMGISGDKLRPKTKKLSISESHESPNKSSPMHERSLSSPIP VIQDSDEAQPGEMGLPSDSLPVNASNEHQGSRTRSPSSDRSRSHHSRISLHDFNFIKVLGKGSFGKVMLA EKKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLM FQIQRARKFDEPRARFYAAEVTLALMFLHRHGIIYRDLKLDNILLDAEGHCKIADFGMCKEGMTENKLTQ TFCGTPDYIAPEILQELKYDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAV SILKGFMTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRKVKPPFKPKIKNKTDANNFDRDFTS EDPVLTPVDPAVIKTINQEEFRGFSFANPDYGKLEMEASGQAH |
| Ensembl Gene | |
|---|---|
| UniGene |
Acl.17890 |
| PDB | |
| RefSeq |
NP_001191401.1 |
| Pfam |
PF00069 PF00130 PF00433 PF00168 |