cytochrome c

General Information (Source: NCBI Gene,UniProt)

Text mining Term cytochrome c
UniProt ID COX2_GALME
Name Cytochrome c oxidase polypeptide II
Cytochrome c oxidase subunit 2
Gene Names COII
Taxonomy Galleria mellonella

General annotation

Function Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
Subcellular location Mitochondrion inner membrane; Multi-pass membrane protein.

Gene Ontology

GO:0070469 respiratory chain CC
GO:0022904 respiratory electron transport chain BP
GO:0005743 mitochondrial inner membrane CC
GO:0016021 integral to membrane CC
GO:0009055 electron carrier activity MF
GO:0005507 copper ion binding MF
GO:0020037 heme binding MF
GO:0004129 cytochrome-c oxidase activity MF

Sequence

>gi|231869|sp|P29874.1|COX2_GALME RecName: Full=Cytochrome c oxidase subunit 2; AltName: Full=Cytochrome c oxidase polypeptide II
MRTWSNFNLQNSASPLMEQIIFFHDHTLIILIMITILVGYIMINLFFNKFINRFFLVGQMIELIWTVLPA
ITLIFIALPSLRLLYLLDELNNPLITLKTIGHQWYWSYEYSDFNNIEFDSYMIASNELPLNNFRLLDVDN
RIILPMNNQIRILVTATDVIHSWTIPSLGVKVDANPGRLNQTNFFINRPGIFYGQCSEICGANHSFMPIV
IESISIKNFINWINNYSY

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF02790
PF00116