Text mining Term | fibrillarin |
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UniProt ID | FBRL_NEUCR |
Name |
rRNA 2'-O-methyltransferase fibrillarin |
Gene Names |
|
Taxonomy | Neurospora crassa OR74A |
Function |
Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'- hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity). |
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Subcellular location |
Nucleus, nucleolus (By similarity). Note=Fibrillar region of the nucleolus (By similarity). |
GO:0006364 | rRNA processing | BP |
GO:0003723 | RNA binding | MF |
GO:0005730 | nucleolus | CC |
GO:0030529 | ribonucleoprotein complex | CC |
GO:0008168 | methyltransferase activity | MF |
GO:0008033 | tRNA processing | BP |
>gi|85103252|ref|XP_961478.1| fibrillarin [Neurospora crassa OR74A] MGFERGGRGGARGGGRGGFGGDRGGRGGARGGSRGGFGGGRGGGAPRGRGGPRGGGRGGATRGRGGARGG AKGGAAGKKVIVEPHRHKGVFVARGGKEDLLATVNLVPGESVYGEKRISVENASKEEGGASTKTEYRIWN PFRSKLAAGILGGLETIYMKPGSKVLYLGAASGTSVSHVADIVGPTGSVYAVEFSHRSGRDLINMATRRT NVIPIVEDARKPMAYRMLLPMVDVIFADVAQPDQARIVGINAKLFLKQGGGLLISIKASCIDSTAPPEQV FASEVQKLREDKFFPKEQLTLEPYERDHAMVSCVYQQKEFVDN |
Ensembl Gene | |
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UniGene |
Ncr.7725 |
PDB | |
RefSeq |
XP_961478.1 |
Pfam |
PF01269 |