transferase

General Information (Source: NCBI Gene,UniProt)

Text mining Term transferase
UniProt ID ANNU_SCHAM
Name Transglutaminase
Protein-glutamine gamma-glutamyltransferase
Annulin
Gene Names
Taxonomy Schistocerca americana

General annotation

Function Participates in morphogenetic activities of the cells, maybe by stabilizing the membrane or subcortical structures of cells that are under mechanical stress. Probably catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Subcellular location Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Intracellular and peripherally associated with the inner leaflet of the cell membrane, using a fatty acid linkage.

Gene Ontology

GO:0003810 protein-glutamine gamma-glutamyltransferase activity MF
GO:0005886 plasma membrane CC
GO:0018149 peptide cross-linking BP
GO:0046872 metal ion binding MF

Sequence

>gi|1703311|sp|P52183.1|ANNU_SCHAM RecName: Full=Annulin; AltName: Full=Protein-glutamine gamma-glutamyltransferase; AltName: Full=Transglutaminase
MGNCCSTFRAVFKPNEGSGGGIPLMPVRGGSTRRPDSLPKPPAAVVPSPPSPGDVPDAGVAPEVASVKEV
DVLLAENGDAHRTRHYELMDREKEPRLVVRRGQPFAVSVTLSRPYNPDIDAISFVFTVEDAEKPSYGQGT
LVAVPLLAKGAESGAAWNAVLDSSADDILRIQITPAADAIVGKWKMDIDTKLKNDGAVSYSYKDPFYILY
NPWCRQDQVFLEGEELLQEYVLNDTGLIWRGSYNRLRPCVWKYAQFEKEILDCALYLVSKIGGVRPSECG
DPVRVCRAISAAVNSPDDNGAVMGNWSNDYGGGTPPTKWIGSMKILQQFYKNKKPVKYGQCWVFAGVLTT
VCRALGLPARTVTTYSAAHDTQNSLTVDYFVDDKGEIMEEMNSDSIWNFHVWTEVWMERPDLMPGDGAHY
GGWQAVDSTPQELSDNMYRCGPAPVVAVKQGEVLRPYDSAYVFAEVNADKVFWRYSGPTQPLKLIRKDML
GIGQNISTKAVGRFQREDITNTYKYPEKSVEERAAMLKALRQSESLFSRYYLNEDFNDIHFNFELRDDIV
IGSPFSVVVVMKNRSNQQDYTVTVLLRVDTVLYTGHVKDGVKKEKVERLIKAGAVEEVRIDVSYEDYYKH
LVDQCAFNIACLATVHDTNYEYFAQDDFRVRKPDIKIKLEGEPVQGQEMSAVATLKNPLPIPVKKGQFLI
EGPGIAKTQKIKLSQNIAPGEEASVNFKFTPKYDGRATIAAKFSSKELDDVDGFLNFMVEPKKEVNGTGN
AA

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF01841
PF00927
PF00868