eukaryotic translation initiation factor 5A

General Information (Source: NCBI Gene,UniProt)

Text mining Term	eukaryotic translation initiation factor 5A
UniProt ID	IF5A_NEUCR
Name	eIF-4D Eukaryotic translation initiation factor 5A eIF-5A
Gene Names
Taxonomy	Neurospora crassa OR74A

General annotation

Function	mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity).
Subcellular location	Cytoplasm (By similarity).

Gene Ontology

GO:0045901	positive regulation of translational elongation	BP
GO:0006452	translational frameshifting	BP
GO:0008612	peptidyl-lysine modification to hypusine	BP
GO:0005737	cytoplasm	CC
GO:0003746	translation elongation factor activity	MF
GO:0045905	positive regulation of translational termination	BP
GO:0043022	ribosome binding	MF

Sequence

>gi|164429238|ref|XP_961911.2| eukaryotic translation initiation factor 5A [Neurospora crassa OR74A]
MSAAHDDAQHEHTFDSVDAGASATYPMQCSALRKGGHVVIKNRPCKIVDMSTSKTGKHGHAKVHLVAIDI
FTGKKLEDLCPSTHNMDVPNVKRTDYQFSYIDEDFLVLIDSNGEEKRDVKMPEGELAKRIEKLEEEGKDF
FVGVQTAMGEEAAIDVKEASNKD

Database Cross Reference

Ensembl Gene
UniGene	Ncr.9233
PDB
RefSeq	XP_961911.2
Pfam	PF00467 PF01287

PTID

eukaryotic translation initiation factor 5A

General Information (Source: NCBI Gene,UniProt)

General annotation

Gene Ontology

Sequence

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Database Cross Reference