gamma tubulin (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term gamma tubulin (protein family or complex)
UniProt ID TBG_SCHPO
Name Gamma-tubulin
Tubulin gamma chain
Gene Names tug1
Synonyms:gtb1
Taxonomy Schizosaccharomyces pombe 972h-

General annotation

Function Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Subcellular location Cytoplasm, cytoskeleton, spindle pole body (Probable).

Gene Ontology

GO:0000070 mitotic sister chromatid segregation BP
GO:0051258 protein polymerization BP
GO:0003924 GTPase activity MF
GO:0005515 protein binding MF
GO:0005874 microtubule CC
GO:0000923 equatorial microtubule organizing center CC
GO:0031122 cytoplasmic microtubule organization BP
GO:0000930 gamma-tubulin complex CC
GO:0010687 site selection involved in cell cycle cytokinesis BP
GO:0005634 nucleus CC
GO:0005525 GTP binding MF
GO:0007020 microtubule nucleation BP
GO:0005816 spindle pole body CC
GO:0007051 spindle organization BP

Sequence

>gi|19112939|ref|NP_596147.1| gamma-tubulin [Schizosaccharomyces pombe 972h-]
MGREIITLQAGQCGNQIGSQFWQQLCLEHGIGPDGTLESFATEGVDRKDVFFYQSDDTRYIPRAILIDLE
PRVVNNILSDTYGSLYNPENILITKNGGGAGNNWANGYSHAERIFEDIMDMIDREADGSDSLEGFSLLHS
IAGGTGSGLGSFLLERLNDRYPKKIIQTYSVFPNSQSVSDVVVQPYNSLLALKRLTLNADSVVVLDNAAL
AHIAADRLHTQNPTFHQQNQLVSTVMSASTTTLRYPGYMNNDLVSIIASLIPSPRCHFLLTSYTPFTNQQ
VEEAKAIRKTTVLDVMRRLLLPKNQMVSVNPSKKSCFISILDIIQGEADPADVHKSLLRIRERRYASFIP
WGPASIQVALSKKSPYIKTNHRVSGLMLANHTSIASLFKRTLDQYDRLRKRNAFLEQYKKEAIFEDDLNE
FDSSRDVVADLINEYEACEDPNYLSL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq NP_596147.1
Pfam PF00091
PF03953