activator protein 1

General Information (Source: NCBI Gene,UniProt)

Text mining Term activator protein 1
UniProt ID FOSLA_DROME
Name Dfos
dFra
Fos-related antigen
Transcription factor kayak, isoforms A/B/F
AP-1
Gene Names kay
Synonyms:Fra
Taxonomy Drosophila melanogaster

General annotation

Function Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra.
Subcellular location Nucleus.

Gene Ontology

GO:0007254 JNK cascade BP
GO:0031660 regulation of cyclin-dependent protein kinase activity involved in G2/M BP
GO:0051124 synaptic growth at neuromuscular junction BP
GO:0046983 protein dimerization activity MF
GO:0035220 wing disc development BP
GO:0005634 nucleus CC
GO:0003700 sequence-specific DNA binding transcription factor activity MF
GO:0042060 wound healing BP
GO:0005737 cytoplasm CC
GO:0007391 dorsal closure BP
GO:0008134 transcription factor binding MF
GO:0046529 imaginal disc fusion, thorax closure BP
GO:0007298 border follicle cell migration BP
GO:0016330 second mitotic wave involved in compound eye morphogenesis BP
GO:0048674 collateral sprouting of injured axon BP
GO:0007464 R3/R4 cell fate commitment BP
GO:0019730 antimicrobial humoral response BP
GO:0043565 sequence-specific DNA binding MF
GO:0006351 transcription, DNA-dependent BP

Sequence

>gi|220903250|gb|AAZ83994.2| kayak, isoform F [Drosophila melanogaster]
MKNLNGRTHNACYHPYYHQSLHFAQQQQQQQQHHLQQQQQHMQQQQQQQQAPQQQLRHQQRQLPTQPAYQ
QSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMP
INYYQQQQQQHYPSESQSSASGWNPETPGQAQLALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNN
HSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCA
GFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDS
TSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQK
RAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRS
DMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDS
LLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGF
GSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVP
IQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dm.6968
PDB
RefSeq NP_001027579.1
NP_001027577.2
NP_001027578.1
Pfam PF00170