NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID C5JUU8_AJEDS
Name NADPH--cytochrome P450 reductase
Gene Names
Taxonomy Ajellomyces dermatitidis SLH14081

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0005506 iron ion binding MF
GO:0010181 FMN binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF

Sequence

>gi|261193391|ref|XP_002623101.1| NADPH-cytochrome P450 reductase [Ajellomyces dermatitidis SLH14081]
MAQVDTLDLVVLIAILVGSVAYFTKGSLWAVVKDPYATSFTTANGAKAGASRDIIEKLNETGKNCVIFFG
SQTGTAEDYASRLAKEGSQRFGLKTMVADLEDYDYENLDKFPEDMVMFFVLATYGEGEPTDNAVDFYQFL
TGEDVAFEGGGGADEKPLSSIKYVAFGLGNNTYEHFNSMVRNVDATMTKLGAKRIGEAGEGDDGAGTMEE
DYLAWKEPMWKALAEEMGLEEREAVYEPVFSVIEEPETSPEADHVYLGEPNSNHLEGQQKGPYHAHNPFI
APIVESRELFTVKDRNCLHMEISVEGSNLSYQTGDHIAIWPTNAGAEVDRFAAVFAITDKRNMVIKIKPL
DVTAKVPFPTPTTYDAVIRYHMEICGPVSRQFIASLATFAPDEASRNEMKRLGSDKDYFQEKIASQYMNI
AQALQSVTPLPFTDVPFSLLIEGIPKIQPRYYSISSSSLLQKHKISVTAIVESLRIPGATHSLKGVTTNY
LLALKQKQHGDPNPDPHGLTYAINGPRNKYDGIHVPVHVRHSNFKLPSDPSKPIIMVGPGTGVAPFRGFI
QERAAQAERGDTVGPTILFYGCRKREEDFLYKDEWETFASKLGSSLQIITAFSRESSKKVYVQHKLREHA
KLVNDLLLQKANFYVCGDAANMAREVNVVLGQIMAEQRGLAPEKGEELVKHMRNNGSYQEDVWS

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_002623101.1
Pfam PF00175
PF00667
PF00258