NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID B6K6E0_SCHJY
Name NADPH--cytochrome P450 reductase
Gene Names
Taxonomy Schizosaccharomyces japonicus yFS275

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0005506 iron ion binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF
GO:0010181 FMN binding MF

Sequence

>gi|213409233|ref|XP_002175387.1| NADPH-cytochrome p450 reductase [Schizosaccharomyces japonicus yFS275]
MSILDILILMAVLAGTAVYFTHGKLWDKPKAQAAAFQGAGESFVEFANENDVKVGVFFGSQTGTAEDYAH
RLAKDITASFGVNAVALDLMDYRFDDLDQLGEDRLVVFVVATYGEGDPTDNATDFMDFIGSDRTEFSNGK
GADEQPLEGIRYAVFGLGNHTYQYYNAMGKKVDACMSTLGATRVGLLGLGDDAEGMLEEDYLEWKEDFLA
DFAGEFELSEKKEEYKPMYRIIEKPEVKSDSPSVFLGELNRQQLQNIPISAPVSSVNPLISCYKKTKELF
KSDNRNCLHIEFDIKDSGLSYKTGDYVSVWPMNPSQAVDDLLDVLGLTAKRNTVIVVQPFNTMDKAPVLS
PTTYDTVFRYYYDICGVVSRQFLSAIAVYAPTAETKAKLEKLGSDKDRFRKTVLDYHLNLAQVLRLVSPN
RPFTNIPFSLLLEDMTHMKPRYYSISSSSLVHPDTVHITAVVSRKEWNEQEHVFYGVATNYLLAHCLHNG
HQKKHHPNGLEYQIDGPRAKWAGGVPVFIKKSNFHLAPPNVPIIMVGPGTGVAPFRAFVMERAKLASDGV
KVAKTVLFYGCQRSNEDFLYADEWKQYKEQMGDAFEMFCAFSREQDHKVYVQHKMLEHADLISDVIDNGG
VFYICGDAERMAKDVTNALAEILTTPKVDGAKRVKELRDNNRFLEDTW

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_002175387.1
Pfam PF00175
PF00258
PF00667