NADPH cytochrome P450 reductase

General Information (Source: NCBI Gene,UniProt)

Text mining Term NADPH cytochrome P450 reductase
UniProt ID F2SI13_TRIRC
Name NADPH--cytochrome P450 reductase
Gene Names
Taxonomy Trichophyton rubrum CBS 118892

General annotation

Function This enzyme is required for electron transfer from NADP to cytochrome P450 (By similarity).
Subcellular location Endoplasmic reticulum membrane (By similarity).

Gene Ontology

GO:0010181 FMN binding MF
GO:0005506 iron ion binding MF
GO:0003958 NADPH-hemoprotein reductase activity MF

Sequence

>gi|327304749|ref|XP_003237066.1| NADPH-cytochrome P450 reductase [Trichophyton rubrum CBS 118892]
MAQVDTLDMLVLAVILVGTIAYFTKGKYWAVVKDPYASSYAATNSAKQGQTRNIVEKLEETGKNCVIFYG
SQTGTAEDYASRLAKEGSQRFGLKTMVADLEDYDYACLDKFPEDKVAFFVLATYGEGEPTDNAVEFFQFI
TGDDASFEDGGSPEDQPLSKMRYVAFGLGNNTYEHYNAMVRIVDKALTKCGAKRIGDAGEGDDGAGTMEE
DYLAWKEPMWKALAEEMGLEEREAIYEPTFSVIEEADLNTESENVYLGEPNSSHLKGRGQGPYNAHNPFL
SPIVESRELFSVKDRNCLHMEFDIKGSQLNYQTGDHIAIWPTNAGQEVDRFLKVFGLEEKRHTVVRVKPI
DVTAKVPFPQPTTYDSVVRYYIETCGPVSRQFISQLAAFAPDEETKKKMIRIGEDKDVFSDKVSAFYFNI
AQALQSFTDKPFTAVPFSLLIEGIPKIQPRYYSISSSSIVQKEKISITAVVESLRVPGAGHVVKGVTTNY
LLALKQKQHGEPNPDPFGLTYAISGPRNKYDGFHVPVHVRHSNFKLPSDPSKPIIMVGPGTGVAPFRGFI
QERVHQAEKGETVGPTILFYGCRKSTEDFLYKEEFEEVSKKLGDSFKLITAFSRETSQKVYVQHRLKEHA
ELVSDLLSKKANFYVCGDAANMAREVNVVLGQILAEQRGLKPEKGEELVKHMRNTGSYQEDVWS

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_003237066.1
Pfam PF00667
PF00258
PF00175