sulfotransferase

General Information (Source: NCBI Gene,UniProt)

Text mining Term sulfotransferase
UniProt ID CHSTF_OMMSL
Name GalNAc4S-6ST
Carbohydrate sulfotransferase 15
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase
Gene Names GALNAC4S6ST
Taxonomy Nototodarus sloanii

General annotation

Function Sulfotransferase that transfers sulfate from 3'- phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units.
Subcellular location Golgi apparatus membrane; Single-pass type II membrane protein (Probable).

Gene Ontology

GO:0000139 Golgi membrane CC
GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity MF

Sequence

>gi|90185281|sp|Q8WTN9.2|CHSTF_OMMSL RecName: Full=Carbohydrate sulfotransferase 15; AltName: Full=N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; Short=GalNAc4S-6ST
SGTTDFYRRIITSEASASTLSLENFXHRVTESINMYEKCFKNETMRKCVYDRSLSLLSGVRLRIGLYWIY
LQDWFSVFPKENFYIIKTEDYAKCLKCTFKKVYRFLGLPQLNRTNEAFMESIPKANTRRFKDTKMGKMWK
ETYELLEKFYQPHNERLVK

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00685