P10

General Information (Source: NCBI Gene,UniProt)

Text mining Term P10
UniProt ID ELBOW_DROME
Name Zinc finger protein Elbow
Gene Names elB
Taxonomy Drosophila melanogaster

General annotation

Function May negatively regulate Notch-induced cell proliferation in the eye-head primordium. May act in leg and wing primordia to negatively regulate body-wall specifying genes and thereby promote appendage formation. Required for tracheal development.
Subcellular location

Gene Ontology

GO:0005515 protein binding MF
GO:0003676 nucleic acid binding MF
GO:0008270 zinc ion binding MF
GO:0035220 wing disc development BP
GO:0007424 open tracheal system development BP
GO:0007219 Notch signaling pathway BP
GO:0005622 intracellular CC
GO:0048737 imaginal disc-derived appendage development BP
GO:0035214 eye-antennal disc development BP
GO:0008283 cell proliferation BP

Sequence

>gi|45445135|gb|AAS64707.1| elbow B, isoform C [Drosophila melanogaster]
MLQSSNHHYLRPDYMTAAAAPTALDNKSSPLALLAQTCSAIGADTTNPKLLAANIEKSTKQLQHHPKGSS
GSGGSGSFGLSQQASMDGSARDKSSPVSSHSSSVSTGSVEQQQLPPAHGSSSSSKPTPTTFKPYEPNNNI
SNITTAADCGATNLSSNNTSAQQRVKTPKSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGG
VMQHNGSPGLPPTASTTPGRSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEANYVKALHA
ASQQGSASAAAAAASYYPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAATP
NVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSGSQGGSGGSSSAAAAAAAAAASS
YHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTHTASVPDAVLSAAAAGGIPPNHPLFQ
RTYPTPPLSPLSAARYHPYGKPSMLPPSLAPPGMPGLPPHPALAQYFAPYSLYGPRMGSSHP

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Database Cross Reference

Ensembl Gene
UniGene Dm.13810
PDB
RefSeq NP_788059.1
NP_523566.3
NP_995712.1
Pfam