| 20066281 |
Rasmussen TS, Jensen HH: Synthesis and glycosidase inhibitory activity of noeurostegine-a new and potent inhibitor of beta-glucoside hydrolases. Org Biomol Chem. 2010 Jan 21;8(2):433-41. Epub 2009 Nov 23.
Sweet almond and Thermotoga maritimabeta-glucosidases, coffee bean alpha-galactosidase, and Asp. oryzaebeta-galactosidase were inhibited in the low micromolar region but significant tightening of binding to K (i) 50 nM for almond beta-glucosidase was found to occur after pre-incubation. |
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