Protein Information

Name CYP2B6
Synonyms CPB 6; CPB6; CYP2B; CYP2B protein; CYP2B6; CYPIIB 6; CYPIIB6; Cytochrome P450 2B6…

Compound Information

Name carbosulfan
CAS

Reference List

PubMed Abstract RScore(About this table)
20307514 Abass K, Reponen P, Mattila S, Pelkonen O: Metabolism of carbosulfan II. Chem Biol Interact. 2010 Mar 20.

Based on average abundances of CYP enzymes in human liver, CYP3A4 contributed to 98% of carbosulfan activation, while CYP3A4 and CYP2B6 contributed 57 and 37% to detoxification, respectively.
87(1,1,2,2) Details