| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | chloranil |
|---|---|
| CAS | 2,3,5,6-tetrachloro-2,5-cyclohexadiene-1,4-dione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6635333 | Dierickx PJ: In vitro binding of 3,4,5,6-tetrachloro-1,2- by rat liver glutathione S-transferases. Res Commun Chem Pathol Pharmacol. 1983 Sep;41(3):517-20. The in vitro interaction of 3,4,5,6-tetrachloro-1,2- (o-chloranil) with rat liver glutathione S-transferases (GST) was studied, using (GSH) and 1-chloro-2,4-dinitrobenzene (CDNB) as substrates. o-Chloranil inhibited the GST activity in crude extracts in a dose dependent manner, while 3,6-dichloro-2,5-dihydroxy- did not. |
32(0,1,1,2) | Details |
| 2714292 | van Ommen B, Ploemen JH, Ruven HJ, Vos RM, Bogaards JJ, van Berkel WJ, van Bladeren PJ: Studies on the active site of rat glutathione S-transferase isoenzyme 4-4. Eur J Biochem. 1989 May 1;181(2):423-9. |
3(0,0,0,3) | Details |
| 3417644 | van Ommen B, den Besten C, Rutten AL, Ploemen JH, Vos RM, Muller F, van Bladeren PJ: Active site-directed irreversible inhibition of glutathione S-transferases by the conjugate of tetrachloro- J Biol Chem. 1988 Sep 15;263(26):12939-42. |
3(0,0,0,3) | Details |
| 8925505 | Jespersen S, Ploemen JH, van Bladeren PJ, Niessen WM, Tjaden UR, van der Greef J: Identification of multiple target sites for a conjugate on glutathione-S-transferase by matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom. 1996 Jan;31(1):101-7. |
2(0,0,0,2) | Details |
| 6523136 | Dierickx PJ: Glutathione S-transferase in aquatic macro-invertebrates and its interaction with different organic micropollutants. Sci Total Environ. 1984 Dec;40:93-102. The interaction of quinones, o-chloranil and chlorophenoxyalkyl acids with the GST activity, in extracts from three different macro-invertebrates, revealed an inhibition which was quite similar to that previously found for rat liver GST. |
2(0,0,0,2) | Details |
| 2043155 | Ploemen JH, van Ommen B, van Bladeren PJ: Irreversible inhibition of human glutathione S-transferase isoenzymes by tetrachloro- and its conjugate. Biochem Pharmacol. 1991 Jun 1;41(11):1665-9. |
2(0,0,0,2) | Details |
| 2069013 | van Ommen B, Bogaards JJ, Ploemen JP, van der Greef J, van Bladeren PJ: Quinones and their conjugates as irreversible inhibitors of glutathione S-transferases. Adv Exp Med Biol. 1991;283:403-6. |
1(0,0,0,1) | Details |
| 7981413 | Fruetel JA, Sparks SE, Quistad GB, Casida JE: Adducts of dienochlor miticide with glutathione S-transferases, and hemoglobins. Chem Res Toxicol. 1994 Jul-Aug;7(4):487-94. |
1(0,0,0,1) | Details |
| 7929428 | Ploemen JH, Johnson WW, Jespersen S, Vanderwall D, van Ommen B, van der Greef J, van Bladeren PJ, Armstrong RN: Active-site tyrosyl residues are targets in the irreversible inhibition of a class Mu glutathione transferase by 2-(S-glutathionyl)-3,5,6-trichloro- J Biol Chem. 1994 Oct 28;269(43):26890-7. The mode of inactivation of glutathione S-transferase isoenzyme 3-3 from rat by the active site-directed inhibitor 2-(S-glutathionyl)-3,5,6-trichloro- (GSTCBQ) has been investigated by a combination of site-specific mutagenesis and mass spectrometric analysis of the sites of reaction of the reagent with the enzyme. |
1(0,0,0,1) | Details |
| 7672422 | McCarthy RM, Sheehan D: plays a role in catalysis in glutathione S-transferase 1-1. Biochem Soc Trans. 1995 May;23(2):388S. |
1(0,0,0,1) | Details |