| Name | glutamine synthetase |
|---|---|
| Synonyms | GLNS; GLUL; GS; Glutamate ammonia ligase; Glutamate ammonia ligase; Glutamine synthase; Glutamine synthetase; PIG43… |
| Name | glufosinate |
|---|---|
| CAS | 2-amino-4-(hydroxymethylphosphinyl)butanoic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19097025 | Pornprom T, Prodmatee N, Chatchawankanphanich O: Glutamine synthetase mutation conferring target-site-based resistance to glufosinate in soybean cell selections. Pest Manag Sci. 2009 Feb;65(2):216-22. |
163(2,2,2,3) | Details |
| 8206444 | Hack R, Ebert E, Ehling G, Leist KH: Glufosinate ammonium--some aspects of its mode of action in mammals. Food Chem Toxicol. 1994 May;32(5):461-70. The broad-spectrum herbicide glufosinate ammonium is a structural analogue of and acts in plants by inhibition of glutamine synthetase leading to a complete breakdown of metabolism. |
163(2,2,2,3) | Details |
| 18562008 | Calas AG, Richard O, Meme S, Beloeil JC, Doan BT, Gefflaut T, Meme W, Crusio WE, Pichon J, Montecot C: Chronic exposure to glufosinate-ammonium induces spatial memory impairments, hippocampal MRI modifications and glutamine synthetase activation in mice. Neurotoxicology. 2008 Jul;29(4):740-7. Epub 2008 May 4. Glufosinate-ammonium (GLA), the active compound of a worldwide-used herbicide, acts by inhibiting the plant glutamine synthetase (GS) leading to a lethal accumulation of |
112(1,2,2,2) | Details |
| 16547651 | Tan S, Evans R, Singh B: Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids. 2006 Mar;30(2):195-204. Epub 2006 Mar 20. Glufosinate inhibits glutamine synthetase and blocks biosynthesis of |
81(1,1,1,1) | Details |
| 7938785 | Hoerlein G: Glufosinate (phosphinothricin), a natural amino acid with unexpected herbicidal properties. Rev Environ Contam Toxicol. 1994;138:73-145. Glufosinate is a structural analog of and inhibits the glutamine synthetase. |
81(1,1,1,1) | Details |
| 18584892 | Qian H, Chen W, Sheng GD, Xu X, Liu W, Fu Z: Effects of glufosinate on antioxidant enzymes, subcellular structure, and gene expression in the unicellular green alga Chlorella vulgaris. Aquat Toxicol. 2008 Jul 30;88(4):301-7. Epub 2008 May 20. Glufosinate, a non-selective herbicide, inhibits glutamine synthetase (GS) and thus blocks ammonium assimilation in plants. |
81(1,1,1,1) | Details |
| 18784206 | Lluis M, Nogue S, Miro O: Severe acute poisoning due to a glufosinate containing preparation without mitochondrial involvement. Hum Exp Toxicol. 2008 Jun;27(6):519-24. Glufosinate toxicity is related to its capacity to inhibit glutamine synthetase and decarboxylase, which may lead to a potentially fatal multiorgan failure. |
81(1,1,1,1) | Details |
| 9121712 | Watanabe T: Apoptosis induced by glufosinate ammonium in the neuroepithelium of developing mouse embryos in culture. Neurosci Lett. 1997 Jan 24;222(1):17-20. Glufosinate ammonium structurally resembles and blocks glutamine synthetase. |
81(1,1,1,1) | Details |
| 16535427 | Franco AR, Lopez-Siles FJ, Cardenas J: Resistance to Phosphinothricin (Glufosinate) and Its Utilization as a Nitrogen Source by Chlamydomonas reinhardtii. Appl Environ Microbiol. 1996 Oct;62(10):3834-3839. Wild-type strain 21gr of the green alga Chlamydomonas reinhardtii was resistant to the ammonium salt of l-phosphinothricin (PPT, also called glufosinate), an irreversible inhibitor of glutamine synthetase activity and the main active component of the herbicide BASTA (AgrEvo, Frankfurt am Main, Germany). |
81(1,1,1,1) | Details |
| 11455628 | Kutlesa NJ, Caveney S: Insecticidal activity of glufosinate through depletion in a caterpillar. Pest Manag Sci. 2001 Jan;57(1):25-32. The herbicide glufosinate-ammonium (GLA) is a competitive inhibitor of glutamine synthetase (GS), an enzyme converting to in both plants and animals. |
81(1,1,1,1) | Details |
| 17273854 | Mohr KI, Tebbe CC: Field study results on the probability and risk of a horizontal gene transfer from transgenic herbicide-resistant oilseed rape pollen to gut bacteria of bees. Appl Microbiol Biotechnol. 2007 Jun;75(3):573-82. Epub 2007 Feb 2. The plants were genetically engineered with the pat-gene, conferring resistance against glufosinate (syn. phosphinothricin), a glutamine-synthetase inhibitor in plants and microorganisms. |
31(0,1,1,1) | Details |
| 12723887 | Miller RP, Martinson KB, Sothern RB, Durgan BR, Gunsolus JL: Circadian response of annual weeds in a natural setting to high and low application rates of four herbicides with different modes of actions. Chronobiol Int. 2003 Mar;20(2):299-324. Four herbicides (GLYT), an amino acid synthesis inhibitor; glufosinate (GLUF), a glutamine synthetase inhibitor; fomesafen (FOME), a protoporphyrinogen oxidase inhibitor, and chlorimuron ethyl (CLIM), an acetolactate synthase inhibitor] were used to examine the influence of time of day of application on the control of a variety of annual broadleaf weeds in field studies conducted in Minnesota (five studies on GLYT and GLUF, three studies on FOME and CLIM). |
31(0,1,1,1) | Details |
| 16510221 | Schulte-Hermann R, Wogan GN, Berry C, Brown NA, Czeizel A, Giavini E, Holmes LB, Kroes R, Nau H, Neubert D, Oesch F, Ott T, Pelkonen O, Robert-Gnansia E, Sullivan FM: Analysis of reproductive toxicity and classification of glufosinate-ammonium. Regul Toxicol Pharmacol. 2006 Apr;44(3 Suppl 1):S1-76. Epub 2006 Feb 28. The mechanism underlying this adverse effect in experimental laboratory animals is identified-inhibition of glutamine synthetase. |
4(0,0,0,4) | Details |
| 10891579 | Yarema C, McLean H, Caveney S: retrieved with the moulting fluid is processed by a glutamine synthetase in the pupal midgut of Calpodes ethlius. J Insect Physiol. 2000 Nov 1;46(11):1497-1507. |
2(0,0,0,2) | Details |
| 19638430 | Meme S, Calas AG, Montecot C, Richard O, Gautier H, Gefflaut T, Doan BT, Meme W, Pichon J, Beloeil JC: MRI characterization of structural mouse brain changes in response to chronic exposure to the glufosinate ammonium herbicide. Toxicol Sci. 2009 Oct;111(2):321-30. Epub 2009 Jul 28. GLA acts by inhibiting the plant glutamine synthetase (GlnS). |
1(0,0,0,1) | Details |
| 10972880 | Masuta C, Yamana T, Tacahashi Y, Uyeda I, Sato M, Ueda S, Matsumura T: Development of clover yellow vein virus as an efficient, stable gene-expression system for legume species. Plant J. 2000 Aug;23(4):539-46. The genes for green fluorescent protein (GFP) and soybean glutamine synthetase (GS) were inserted between the genes for P1 and HC-Pro on pClYVV to create three recombinant plasmids: pClYVV-GFP, pClYVV-GFP-GS, and pClYVV-GFP:GS. The plants expressing GS together with GFP became tolerant to the herbicide glufosinate, and flowered early. |
1(0,0,0,1) | Details |