Name | ATPase |
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Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
Name | copper sulfate |
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CAS | sulfuric acid copper(2+) salt (1:1) |
PubMed | Abstract | RScore(About this table) | |
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18831375 | Mathur S, Gupta AK: Histoenzymological study on the toxicity of On the other hand, same area of the gland showed moderate activity of ATPase during 24 and 48 hr of exposure. |
sulphate in the digestive glands of Lymnaea luteola. J Environ Biol. 2008 Mar;29(2):201-4.1(0,0,0,1) | Details |
15836927 | Qian Y, Zheng Y, Abraham L, Ramos KS, Tiffany-Castiglioni E: Differential profiles of neuroblastoma and astrocytoma cells. Brain Res Mol Brain Res. 2005 Apr 4;134(2):323-32. Epub 2005 Jan 13. Intracellular Cu levels as determined by inductively coupled plasma-mass spectrometry (ICP-MS), and expression levels of -transporting ATPase (ATP7A) and human copper transporter 1 (hCtr1) as detected by quantitative reverse transcription-polymerase chain reaction (RT-PCR), were comparable in both cell lines. |
-induced ROS generation in human 1(0,0,0,1) | Details |
12579329 | Harada M, Kumemura H, Sakisaka S, Shishido S, Taniguchi E, Kawaguchi T, Hanada S, Koga H, Kumashiro R, Ueno T, Suganuma T, Furuta K, Namba M, Sugiyama T, Sata M: Wilson disease protein ATP7B is localized in the late endosomes in a polarized human hepatocyte cell line. Int J Mol Med. 2003 Mar;11(3):293-8. The effects of bathocuproine disulfonate, a chelator, and copper sulfate were examined. |
1(0,0,0,1) | Details |
18987288 | Craig PM, Galus M, Wood CM, McClelland GB: Dietary iron alters waterborne Gene expression levels for divalent metal transport (DMT)-1, copper transporter (CTR)-1, and the basolateral metal transporter ATP7A in the gills and gut increased when compared with controls, but the various combinations of Cu and high-Fe diet revealed altered levels of expression. |
-induced gene expression in soft water acclimated zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2009 Feb;296(2):R362-73. Epub 2008 Nov 5.1(0,0,0,1) | Details |
8717422 | Lal S, Chithra P, Chandrakasan G: The possible relevance of autoxidative glycosylation in mediated alterations of proteins: an in vitro study on myofibrillar proteins. Mol Cell Biochem. 1996 Jan 26;154(2):95-100. A significant increase in extent of glycation and decrease in ATPase activity of myofibrils incubated under autoxidative conditions were observed over the other three incubations. |
1(0,0,0,1) | Details |
18707611 | Zhang XX, Rainey PB: Regulation of Pseudomonas fluorescens SBW25. Environ Microbiol. 2008 Dec;10(12):3284-94. Epub 2008 Aug 14. When growing on plant surfaces, the plant growth-promoting bacterium Pseudomonas fluorescens SBW25 activates expression of a -transporting P1-type ATPase (CueA). Resistance to exogenously applied copper sulfate shows that cueA and cueR mutants are significantly less resistant than the wild type. |
homeostasis in 1(0,0,0,1) | Details |
11959576 | Hasman H, Aarestrup FM: tcrB, a gene conferring transferable linkage to macrolide and glycopeptide resistance. Antimicrob Agents Chemother. 2002 May;46(5):1410-6. The tcrB gene encodes a putative protein belonging to the CPx-type ATPase family with homology (46%) to the CopB protein from Enterococcus hirae. The frequent occurrence of this new resistance gene in isolates from pigs, where copper sulfate is being used in large amounts as feed additive, suggests that the use of has selected for resistance. |
resistance in Enterococcus faecium: occurrence, transferability, and 1(0,0,0,1) | Details |
1288347 | Odermatt A, Suter H, Krapf R, Solioz M: An ATPase operon involved in resistance by Enterococcus hirae. Ann N Y Acad Sci. 1992 Nov 30;671:484-6. |
1(0,0,0,1) | Details |
8670305 | Wojtczak L, Nikitina ER, Czyz A, Skulskii IA: Cuprous ions activate glibenclamide-sensitive potassium channel in liver mitochondria. Biochem Biophys Res Commun. 1996 Jun 14;223(2):468-73. In K (+)-containing media, Cu+ collapsed the mitochondrial membrane potential formed by operation of the respiratory chain with or tetramethyl p-phenylenediamine + as substrates or by the -pumping ATPase. |
1(0,0,0,1) | Details |
8048974 | Odermatt A, Suter H, Krapf R, Solioz M: Primary structure of two P-type ATPases involved in homeostasis in Enterococcus hirae. J Biol Chem. 1993 Jun 15;268(17):12775-9. CopA exhibits 35% sequence similarity to CopB and 43% similarity to the ATPase encoded by the recently cloned human Mc1 gene, a gene responsible for the Menkes inborn error of metabolism. |
1(0,0,0,1) | Details |
17728190 | Garcia Sampaio F, de Lima Boijink C, Tie Oba E, Romagueira Bichara dos Santos L, Lucia Kalinin A, Tadeu Rantin F: Antioxidant defenses and biochemical changes in pacu (Piaractus mesopotamicus) in response to single and combined hypoxia exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2008 Jan;147(1):43-51. Epub 2007 Aug 1. Na (+)/K (+)-ATPase activity in gills decreased in 0.4Cu and 0.4CuHpx, and increased in Hpx. |
and 1(0,0,0,1) | Details |
10915804 | Outten FW, Outten CE, Hale J, O'Halloran TV: Transcriptional activation of an Escherichia coli CopA, the principal efflux ATPase in Escherichia coli, is induced by elevated in the medium, but the -sensing regulatory factor is unknown. |
efflux regulon by the chromosomal MerR homologue, cueR. J Biol Chem. 2000 Oct 6;275(40):31024-9.1(0,0,0,1) | Details |
10593600 | Vasic V, Jovanovic D, Krstic D, Nikezic G, Horvat A, Vujisic L, Nedeljkovic N: Prevention and recovery of CuSO4-induced inhibition of Na+/K+ -ATPase and Mg2+ -ATPase in rat brain synaptosomes by EDTA. Toxicol Lett. 1999 Oct 29;110(1-2):95-104. |
5(0,0,0,5) | Details |
17158254 | Nyasae L, Bustos R, Braiterman L, Eipper B, Hubbard A: Dynamics of endogenous ATP7A (Menkes protein) in intestinal epithelial cells: -dependent redistribution between two intracellular sites. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1181-94. Epub 2006 Dec 7. |
5(0,0,0,5) | Details |
17695505 | Matsumoto S, Tanaka T, Kurokawa H, Matsuno K, Hayashida Y, Takahashi T: Effect of ATP7A and CTR1 in intracellular accumulation of cisplatin. Anticancer Res. 2007 Jul-Aug;27(4B):2209-16. |
and role of the transporters 4(0,0,0,4) | Details |
10816044 | Fernandes AR, Prieto M, Sa-Correia I: Modification of plasma membrane lipid order and H+-ATPase activity as part of the response of Saccharomyces cerevisiae to cultivation under mild and high stress. Arch Microbiol. 2000 Apr;173(4):262-8. |
4(0,0,0,4) | Details |
12782727 | Shikanai T, Muller-Moule P, Munekage Y, Niyogi KK, Pilon M: PAA1, a P-type ATPase of Arabidopsis, functions in transport in chloroplasts. Plant Cell. 2003 Jun;15(6):1333-46. |
2(0,0,0,2) | Details |
7592871 | Sarvazyan NA, Modyanov NN, Askari A: Intersubunit and intrasubunit contact regions of Na+/K (+)-ATPase revealed by controlled proteolysis and chemical cross-linking. J Biol Chem. 1995 Nov 3;270(44):26528-32. |
2(0,0,0,2) | Details |
16773204 | Plasencia C, Martinez-Balibrea E, Martinez-Cardus A, Quinn DI, Abad A, Neamati N: Expression analysis of genes involved in oxaliplatin response and development of oxaliplatin-resistant HT29 colon cancer cells. Int J Oncol. 2006 Jul;29(1):225-35. Our data also confirmed that transporters and chaperones are involved in OXA resistance in colorectal cancer cells as evidenced by the overexpression of ATP7A and CCS in response to OXA exposure. |
2(0,0,0,2) | Details |
15681833 | Harada M, Kawaguchi T, Kumemura H, Terada K, Ninomiya H, Taniguchi E, Hanada S, Baba S, Maeyama M, Koga H, Ueno T, Furuta K, Suganuma T, Sugiyama T, Sata M: The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein. Am J Pathol. 2005 Feb;166(2):499-510. |
2(0,0,0,2) | Details |
10940034 | Riggle PJ, Kumamoto CA: Role of a Candida albicans P1-type ATPase in resistance to and silver ion toxicity. J Bacteriol. 2000 Sep;182(17):4899-905. |
2(0,0,0,2) | Details |
19033537 | Braiterman L, Nyasae L, Guo Y, Bustos R, Lutsenko S, Hubbard A: Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the ATPase, ATP7B. Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G433-44. Epub 2008 Nov 25. |
-2(0,0,0,2) | Details |
20213433 | Sampaio FG, de Lima Boijink C, Dos Santos LR, Oba ET, Kalinin AL, Rantin FT: The combined effect of Copper sulfate is widely used in aquaculture. Exposure to 0.4Cu and 0.4CupH resulted in a reduction in the Na (+)/K (+)-ATPase activity and an increase in metallothionein (MT) in the gills. |
and low pH on antioxidant defenses and biochemical parameters in neotropical fish pacu, Piaractus mesopotamicus (Holmberg, 1887). Ecotoxicology. 2010 Mar 6.2(0,0,0,2) | Details |