| Name | NK1 |
|---|---|
| Synonyms | BY55; CD160; CD160 antigen; CD160 antigen precursor; CD160 molecule; NK1; NK28; Natural killer cell receptor BY55… |
| Name | copper sulfate |
|---|---|
| CAS | sulfuric acid copper(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8813551 | Gonsalves S, Watson J, Ashton C: Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets. Eur J Pharmacol. 1996 Jun 3;305(1-3):181-5. The potent, selective, tachykinin NK1 receptor antagonist, CP-122,721 ([(+)-(2S,3S)-3-(2-methoxy-5-trifluoromethoxybenzyl) amino-2- phenylpiperidine]), at 0.01-1 mg/kg, s.c. reduced retching and vomiting elicited by copper sulfate, ipecac syrup and cisplatin in a dose-dependent manner. |
33(0,1,1,3) | Details |
| 10082206 | Rudd JA, Ngan MP, Wai MK: Inhibition of emesis by tachykinin NK1 receptor antagonists in Suncus murinus (house musk shrew). Eur J Pharmacol. 1999 Feb 5;366(2-3):243-52. |
3(0,0,0,3) | Details |
| 15528840 | Nakayama H, Yamakuni H, Nakayama A, Maeda Y, Imazumi K, Matsuo M, Mutoh S: Diphenidol has no actual broad antiemetic activity in dogs and ferrets. J Pharmacol Sci. 2004 Nov;96(3):301-6. Epub 2004 Nov 5. In ferrets, diphenidol (10 mg/kg, i.p.) exhibited a weak antiemetic activity on the emesis induced by copper sulfate and had no activity on emesis by On the other hand, CP-122,721, a NK1-receptor antagonist, significantly reduced the emetic episodes to all four stimuli. |
1(0,0,0,1) | Details |
| 17254564 | Chan SW, Rudd JA, Lin G, Li P: Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew). Eur J Pharmacol. 2007 Mar 22;559(2-3):196-201. Epub 2006 Dec 29. Tachykinin NK1 receptor antagonists and 5-HT1A receptor agonists are examples of centrally acting drugs that reduce cough and emesis. |
1(0,0,0,1) | Details |