| Name | polymerases |
|---|---|
| Synonyms | ERVK 2; ERVK2; HERV K; Polymerase; Polymerases |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16101492 | Pommier Y, Marchand C: Interfacial inhibitors of protein-nucleic acid interactions. . Curr Med Chem Anticancer Agents. 2005 Jul;5(4):421-9. We will also provide examples generalizing the interfacial inhibitor concept to inhibitors of topoisomerase II (anthracyclines, ellipticines, epipodophyllotoxins), gyrase (quinolones, ciprofloxacin, norfloxacin), RNA polymerases (alpha-amanitin and actinomycin D), and ribosomes (antibiotics such as streptomycin, hygromycin B, tetracycline, kirromycin, thiostrepton, and possibly cycloheximide). |
31(0,1,1,1) | Details |
| 15721989 | Cervantes-Laurean D, Roberts MJ, Jacobson EL, Jacobson MK: Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment. Free Radic Biol Med. 2005 Mar 15;38(6):786-95. The increase also was unaffected by inhibitors of poly (ADP- polymerases, which have been previously implicated in nuclear proteasome activation by oxidizing agents. |
1(0,0,0,1) | Details |
| 17698581 | Shen C, Lancaster CS, Shi B, Guo H, Thimmaiah P, Bjornsti MA: TOR signaling is a determinant of cell survival in response to DNA damage. Mol Cell Biol. 2007 Oct;27(20):7007-17. Epub 2007 Aug 13. Our findings support a model whereby TORC1 acts as a survival pathway in response to genotoxic stress by maintaining the deoxynucleoside pools necessary for error-prone translesion DNA polymerases. |
1(0,0,0,1) | Details |
| 19684113 | Huber A, Bodenmiller B, Uotila A, Stahl M, Wanka S, Gerrits B, Aebersold R, Loewith R: Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev. 2009 Aug 15;23(16):1929-43. Follow-up detailed characterization shows that Sch9 regulates RNA polymerases I and III, the latter via Maf1, in addition to translation initiation and the expression of ribosomal protein and ribosome biogenesis genes. |
1(0,0,0,1) | Details |
| 16358735 | Smirnova AN, Krutilina RI, Tomilin NV: [Dynamic binding of the telomeric human protein TRF1 to intrachromosomal blocks (TTAGGG) n in living Chinese hamster cells depends on transcription]. Mol Biol. 2005 Nov-Dec;39(6):978-83. Treatment of the cells with transcription inhibitor actinomycin D (ActD) in the concentration completely inhibiting activity of DNA-dependent RNA polymerases I and II (RPI and RPII) leads to fast and practically full suppression of exchange GFP-TRF1 (10% of initial fluorescence is restored only) whereas an inhibitor of protein synthesis cycloheximide (CHD) has not effect. |
0(0,0,0,0) | Details |