| Name | TNFR1 |
|---|---|
| Synonyms | CD120a; P55; TBP1; p60; CD120a antigen; FPF; TNF R; TNF R I… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15545300 | Jaruga-Killeen E, Rayford W: TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3. FASEB J. 2005 Jan;19(1):139-41. Epub 2004 Nov 15. Cell cycle and typical markers of apoptosis were analyzed by flow cytometry in the presence of the following reagents: cycloheximide, pan-caspase inhibitor ZVAD-fmk, neutralizing anti-TNFR1, and anti-TNFR2. |
83(1,1,1,3) | Details |
| 18180277 | Stojanov S, Dejaco C, Lohse P, Huss K, Duftner C, Belohradsky BH, Herold M, Schirmer M: Clinical and functional characterisation of a novel TNFRSF1A c.605T> A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercept treatment. Ann Rheum Dis. 2008 Sep;67(9):1292-8. Epub 2008 Jan 7. Apoptosis of PBMCs was studied by stimulation with TNFalpha in the presence of cycloheximide and annexin V staining. |
7(0,0,0,7) | Details |
| 16508982 | D'Osualdo A, Ferlito F, Prigione I, Obici L, Meini A, Zulian F, Pontillo A, Corona F, Barcellona R, Di Duca M, Santamaria G, Traverso F, Picco P, Baldi M, Plebani A, Ravazzolo R, Ceccherini I, Martini A, Gattorno M: Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications. Arthritis Rheum. 2006 Mar;54(3):998-1008. Neutrophils were isolated from heparinized blood by dextran sedimentation and incubated with and without cycloheximide (CHX) and TNFalpha. |
4(0,0,0,4) | Details |
| 15657078 | Depuydt B, van Loo G, Vandenabeele P, Declercq W: Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors. J Cell Sci. 2005 Feb 1;118(Pt 3):497-504. Epub 2005 Jan 18. Previously we reported that both human TNFR1 and TNFR2 mediate TNF-induced apoptosis in the transfected rat/mouse T cell hybridoma PC60. |
3(0,0,0,3) | Details |
| 16940541 | Sedger LM, Osvath SR, Xu XM, Li G, Chan FK, Barrett JW, McFadden G: Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death. J Virol. 2006 Sep;80(18):9300-9. Jurkat cell lines constitutively expressing M-T2 were generated and shown to be resistant to UV irradiation-, etoposide-, and cycloheximide-induced death. |
2(0,0,0,2) | Details |
| 19289468 | Kurada BR, Li LC, Mulherkar N, Subramanian M, Prasad KV, Prabhakar BS: MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment. J Biol Chem. 2009 May 15;284(20):13533-41. Epub 2009 Mar 16. We investigated the physiological role of endogenous MAPK-activating death domain-containing protein (MADD), a splice variant of the IG20 gene, that can interact with TNFR1 in tumor necrosis factor-alpha (TNFalpha)-induced activation of NF-kappaB, MAPK, ERK1/2, JNK, and p38. Abrogation of MADD expression rendered cells highly susceptible to TNFalpha-induced apoptosis in the absence of cycloheximide. |
2(0,0,0,2) | Details |
| 19473970 | Ding B, Kirkiles-Smith NC, Pober JS: FOXO3a regulates -responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells. J Biol Chem. 2009 Jul 17;284(29):19331-9. Epub 2009 May 27. TNFR1 expression is unaffected by hypoxia or reoxygenation in these same cells. |
2(0,0,0,2) | Details |
| 17614795 | Aufiero B, Guo M, Young C, Duanmu Z, Talwar H, Lee HK, Murakawa GJ: Staphylococcus aureus induces the expression of tumor necrosis factor-alpha in primary human keratinocytes. Int J Dermatol. 2007 Jul;46(7):687-94. Finally, S. aureus infection of primary human keratinocytes also led to an induction of the TNF-alpha receptor, TNFR1 (p55). |
1(0,0,0,1) | Details |
| 19664126 | Misiak-Tloczek A, Brzezinska-Blaszczyk E: IL-6, but not IL-4, stimulates chemokinesis and TNF stimulates chemotaxis of tissue mast cells: involvement of both mitogen-activated protein kinases and phosphatidylinositol 3-kinase signalling pathways. APMIS. 2009 Aug;117(8):558-67. Mast cell migratory responses to IL-6 and TNF were entirely blocked by specific anti-IL-6R and anti-TNFR1 antibodies. |
1(0,0,0,1) | Details |