| Name | Nerve growth factor |
|---|---|
| Synonyms | Beta NGF; Beta nerve growth factor; Beta nerve growth factor precursor; HSAN 5; HSAN5; NGF; NGFB; Nerve growth factor… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14598305 | Turner BJ, Rembach A, Spark R, Lopes EC, Cheema SS: Opposing effects of low and high-dose clozapine on survival of transgenic amyotrophic lateral sclerosis mice. J Neurosci Res. 2003 Nov 15;74(4):605-13. Furthermore, low concentrations of clozapine protected NSC-34 cells from paraquat-mediated toxicity, nerve growth factor (NGF)-induced death signalling, and serum deprivation, whereas high concentrations potentiated death. |
81(1,1,1,1) | Details |
| 16936100 | Schlieve CR, Lieven CJ, Levin LA: Biochemical activity of reactive species scavengers do not predict retinal ganglion cell survival. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3878-86. Last, H2O2 induced intramitochondrial O2-, whereas paraquat produced O2- outside of the mitochondria, and these areas of generation can mislead interpretations of ROS scavenger activity and effectiveness. Reactive species (ROS) act as intracellular signaling molecules and initiate apoptosis in nerve growth factor-deprived sympathetic neurons and axotomized RGCs. |
1(0,0,0,1) | Details |