Protein Information

Name PAR2
Synonyms G protein coupled receptor 42; GPCR; PAR2; G protein coupled receptor 172B; GPCR42; GPR172B; PERV A receptor 2; Porcine endogenous retrovirus A receptor 2…

Compound Information

Name paraquat
CAS 1,1′-dimethyl-4,4′-bipyridinium

Reference List

PubMed Abstract RScore(About this table)
19806166 Chen R, Sun S, Wang C, Li Y, Liang Y, An F, Li C, Dong H, Yang X, Zhang J, Zuo J: The Arabidopsis PARAQUAT RESISTANT2 gene encodes an S-nitrosoglutathione reductase that is a key regulator of cell death. Cell Res. 2009 Dec;19(12):1377-87. Epub 2009 Oct 6.

The production of superoxide in par2-1 is comparable to that of wild-type plants when treated by paraquat (1,1'-dimethyl-4,4'-bipyridinium dichloride), suggesting that PAR2 acts downstream of superoxide to regulate cell death.
32(0,1,1,2) Details