| Name | NK 1 receptor |
|---|---|
| Synonyms | NK 1 receptor; NK 1R; NK1R; NKIR; Neurokinin 1 receptor; SPR; Substance P Receptor; TAC1R… |
| Name | copper sulfate |
|---|---|
| CAS | sulfuric acid copper(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10629882 | Saito R, Ariumi H, Kubota H, Nago S, Honda K, Takano Y, Kamiya H: [The role of tachykinin NK-1 receptors in emetic action in the area postrema of ferrets]. Nippon Yakurigaku Zasshi. 1999 Oct;114 Suppl 1:209P-214P. Substance P (SP) is a member of the tachykinin family of bioactive peptides and has highest affinity for the NK-1 receptor. |
2(0,0,0,2) | Details |
| 10688616 | Yamakuni H, Sawai H, Maeda Y, Imazumi K, Sakuma H, Matsuo M, Mutoh S, Seki J: Probable involvement of the 5-hydroxytryptamine (4) receptor in methotrexate-induced delayed emesis in dogs. J Pharmacol Exp Ther. 2000 Mar;292(3):1002-7. CP-122,721 (0. 1 mg/kg), a potent selective tachykinin NK (1) receptor antagonist, significantly reduced the emetic responses to MTX. Copper sulfate-induced emesis in dogs was also prevented by FK1052, tropisetron, and CP-122,721 but not by |
2(0,0,0,2) | Details |
| 10214984 | Saito R, Suehiro Y, Ariumi H, Migita K, Hori N, Hashiguchi T, Sakai M, Saeki M, Takano Y, Kamiya H: Anti-emetic effects of a novel NK-1 receptor antagonist HSP-117 in ferrets. Neurosci Lett. 1998 Oct 2;254(3):169-72. |
2(0,0,0,2) | Details |
| 10825652 | Ariumi H, Saito R, Nago S, Hyakusoku M, Takano Y, Kamiya H: The role of tachykinin NK-1 receptors in the area postrema of ferrets in emesis. Neurosci Lett. 2000 Jun 2;286(2):123-6. Pretreatment with the tachykinin NK-1 receptor antagonists HSP-117 (1.0 microg) and CP-99,994 (7.5 microg) into the AP decreased the numbers of vomits and retches induced by morphine and sulphate. |
1(0,0,0,1) | Details |
| 11698156 | Andrews PL, Kovacs M, Watson JW: The anti-emetic action of the neurokinin (1) receptor antagonist CP-99,994 does not require the presence of the area postrema in the dog. Neurosci Lett. 2001 Nov 13;314(1-2):102-4. In AP ablated animals the selective NK (1) receptor antagonist CP-99, 994 (1 mg kg (-1) i.v.) blocked the emetic response to sulphate as it did in intact animals. |
1(0,0,0,1) | Details |