Name | cathepsin B |
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Synonyms | APP secretase; APPS; Amyloid precursor protein secretase; CPSB; CTSB; Cathepsin B; Cathepsin B precursor; Cathepsin B1… |
Name | phosphine |
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CAS | phosphine |
PubMed | Abstract | RScore(About this table) | |
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18164406 | Gunatilleke SS, Barrios AM: Tuning the Au (I)-mediated inhibition of cathepsin B through ligand substitutions. J Inorg Biochem. 2008 Mar;102(3):555-63. Epub 2007 Nov 22. In this study, the extent to which the steric and electronic properties of the phosphine ligand can be modified to obtain enhanced potency against cathepsin B is investigated. |
83(1,1,1,3) | Details |
18253767 | Gunatilleke SS, de Oliveira CA, McCammon JA, Barrios AM: Inhibition of cathepsin B by Au (I) complexes: a kinetic and computational study. J Biol Inorg Chem. 2008 May;13(4):555-61. Here we employ a combination of experimental and computational investigations into the effect of changes in the phosphine ligand of auranofin on its in vitro inhibition of cathepsin B. |
82(1,1,1,2) | Details |