| 17175555 |
Cha'on U, Valmas N, Collins PJ, Reilly PE, Hammock BD, Ebert PR: Disruption of iron homeostasis increases phosphine toxicity in Caenorhabditis elegans. Toxicol Sci. 2007 Mar;96(1):194-201. Epub 2006 Dec 14.
In this report, we demonstrate the following dose-dependent actions of phosphine, in vitro: (1) reduction of ferric iron (Fe3+) to ferrous iron (Fe2+), (2) release of iron from horse ferritin, (3) and the peroxidation of lipid as a result of iron release from ferritin. |
120(1,2,3,5) |
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