| 19541826 |
Mazur CS, Kenneke JF, Goldsmith MR, Brown C: Contrasting influence of NADPH and a NADPH-regenerating system on the metabolism of carbonyl-containing compounds in hepatic microsomes. Drug Metab Dispos. 2009 Sep;37(9):1801-5. Epub 2009 Jun 18.
In this study, we compared the effects of direct addition of NADPH and use of an NRS on the P450-mediated transformation of propiconazole and 11 beta-hydroxysteroid dehydrogenase type 1 (HSD1) carbonyl reduction of cortisone and the xenobiotic triadimefon in hepatic microsomes. |
31(0,1,1,1) |
Details |