| PubMed |
Abstract |
RScore(About this table) |
| 9071579 |
Evans DR, Stark MJ: Mutations in the Saccharomyces cerevisiae type 2A protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis. Genetics. 1997 Feb;145(2):227-41.
Ts- pph22 mutant cells also accumulated aberrant microtubule structures at 37 degrees, while under semi-permissive conditions they were sensitive to the microtubule-destabilizing agent benomyl, suggesting that PP2A is required for normal microtubule function. |
34(0,1,1,4) |
Details |
| 11470822 |
Kornitzer D, Sharf R, Kleinberger T: Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome. J Cell Biol. 2001 Jul 23;154(2):331-44.
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4(0,0,0,4) |
Details |
| 11129046 |
Evans DR, Hemmings BA: Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae. Mol Gen Genet. 2000 Nov;264(4):425-32.
These results demonstrate that the regulation of PP2A, mediated by PR55/B binding to the highly conserved PP2Ac C-terminus, is critical for cell viability under conditions of microtubule damage and support a role for PP2A in exit from mitosis. |
1(0,0,0,1) |
Details |