Name | S12 |
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Synonyms | 5 HT 1B; S12; 5 HT 1D beta; 5 HT1B; 5 HT1DB; 5 hydroxytryptamine (serotonin) receptor 1B; 5 hydroxytryptamine 1B receptor; HTR1B… |
Name | kasugamycin |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19187763 | Kaberdina AC, Szaflarski W, Nierhaus KH, Moll I: An unexpected type of ribosomes induced by kasugamycin: a look into ancestral times of protein synthesis?. Mol Cell. 2009 Jan 30;33(2):227-36. Unexpected from the known in vitro effects of the drug, kasugamycin induced the formation of stable approximately 61S ribosomes in vivo, which were proficient in selectively translating leaderless mRNA. 61S particles are devoid of more than six proteins of the small subunit, including the functionally important proteins S1 and S12. |
6(0,0,1,1) | Details |
765762 | Saltzman L, Apirion D: Binding of erythromycin to the 50S ribosomal subunit is affected by alterations in the 30S ribosomal subunit. Mol Gen Genet. 1976 Feb 2;143(3):301-6. Expression of resistance to erythromycin in Escherichia coli, caused by an altered L4 protein in the 50S ribosomal subunit, can be masked when two additional ribosomal mutations affecting the 30S proteins S5 and S12 are introduced into the strain (Saltzman, Brown, and Apriion, 1974). Among mutants isolated for the reappearance of erythromycin resistance, kasugamycin resistant mutants were found. |
2(0,0,0,2) | Details |