Protein Information

Name transferase
Synonyms 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80…

Compound Information

Name kasugamycin
CAS

Reference List

PubMed Abstract RScore(About this table)
6440121 Van Buul CP, Hamersma M, Visser W, Van Knippenberg PH: Partial methylation of two adjacent adenosines in ribosomes from Euglena gracilis chloroplasts suggests evolutionary loss of an intermediate stage in the methyl-transfer reaction. Nucleic Acids Res. 1984 Dec 11;12(23):9205-8.

The methylation reaction was studied in vitro using ribosomes from a kasugamycin resistant mutant (ksgA) of Escherichia coli and purified methyl-transferase.
31(0,1,1,1) Details
14526028 Sabina J, Dover N, Templeton LJ, Smulski DR, Soll D, LaRossa RA: Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12. J Bacteriol. 2003 Oct;185(20):6158-70.

Treatment with kasugamycin and puromycin (targeting ribosomal subunit association as well as its peptidyl-transferase activity) caused accumulation of mRNAs from ribosomal protein operons.
6(0,0,1,1) Details