| Name | gamma tubulin (protein family or complex) |
|---|---|
| Synonyms | Gamma tubulin; Gamma tubulin complex; Gamma tubulins |
| Name | benomyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8089179 | Horio T, Oakley BR: Human gamma-tubulin functions in fission yeast. J Cell Biol. 1994 Sep;126(6):1465-73. Finally, we have found that expression of human gamma-tubulin or overexpression of S. pombe gamma-tubulin causes no significant alteration of resistance to the antimicrotubule agents benomyl, thiabendazole and nocodazole. |
8(0,0,0,8) | Details |
| 11452008 | Jung MK, Prigozhina N, Oakley CE, Nogales E, Oakley BR: -scanning mutagenesis of Aspergillus gamma-tubulin yields diverse and novel phenotypes. Mol Biol Cell. 2001 Jul;12(7):2119-36. The cold sensitivity of two alleles is strongly suppressed by the antimicrotubule agents benomyl and nocodazole and a third allele is essentially dependent on these compounds for growth. |
5(0,0,0,5) | Details |
| 14668489 | Prigozhina NL, Oakley CE, Lewis AM, Nayak T, Osmani SA, Oakley BR: gamma-tubulin plays an essential role in the coordination of mitotic events. Mol Biol Cell. 2004 Mar;15(3):1374-86. Epub 2003 Dec 10. In experiments in which microtubules were depolymerized with benomyl, mipAD159 nuclei exited mitosis significantly more quickly (as judged by chromosomal condensation) than nuclei in a control strain. |
4(0,0,0,4) | Details |
| 11034914 | Vogel J, Snyder M: The carboxy terminus of Tub4p is required for gamma-tubulin function in budding yeast. J Cell Sci. 2000 Nov;113 Pt 21:3871-82. Growth defects of tub4 mutants lacking either or both carboxy-terminal domains are suppressed by the microtubule destabilizing drug benomyl. tub4 carboxy-terminal mutants arrest as large budded cells with short bipolar spindles positioned at the bud neck. |
3(0,0,0,3) | Details |
| 11709183 | Vogel J, Drapkin B, Oomen J, Beach D, Bloom K, Snyder M: Phosphorylation of gamma-tubulin regulates microtubule organization in budding yeast. Dev Cell. 2001 Nov;1(5):621-31. |
3(0,0,0,3) | Details |
| 9463374 | Geissler S, Siegers K, Schiebel E: A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J. 1998 Feb 16;17(4):952-66. The disruption of any of these genes results in similar phenotypes: the gim null mutants are synthetically lethal with tub4-1 and super-sensitive towards the microtubule-depolymerizing drug benomyl. |
3(0,0,0,3) | Details |
| 15930134 | Li S, Oakley CE, Chen G, Han X, Oakley BR, Xiang X: Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans. Mol Biol Cell. 2005 Aug;16(8):3591-605. Epub 2005 Jun 1. In the presence of a low amount of benomyl, a microtubule-depolymerizing agent, however, a dynein mutant diploid strain exhibits a more pronounced chromosome loss phenotype than the control, indicating that cytoplasmic dynein plays a role in chromosome segregation. |
2(0,0,0,2) | Details |
| 16672380 | Fink G, Steinberg G: Dynein-dependent motility of microtubules and nucleation sites supports polarization of the tubulin array in the fungus Ustilago maydis. Mol Biol Cell. 2006 Jul;17(7):3242-53. Epub 2006 May 3. In budding cells, most MTs are nucleated by three to six small and motile gamma-tubulin-containing MTOCs at the boundary of mother and daughter cell, which results in a polarized MT array. Disruption of MTs with benomyl and subsequent washout led to an equal distribution of the MTOC and random formation of highly motile and randomly oriented MTs throughout the cytoplasm. |
1(0,0,0,1) | Details |