Protein Information

Name LHRH
Synonyms GNRH; GNRH 1; GNRH1; GRH; GnRH associated peptide I; Gonadoliberin I; Gonadorelin; Gonadotropin releasing hormone 1…

Compound Information

Name carvone
CAS 2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
9892469 Bhatia KS, Singh J: Mechanism of transport enhancement of LHRH through porcine epidermis by terpenes and iontophoresis: permeability and lipid extraction studies. Pharm Res. 1998 Dec;15(12):1857-62.

PURPOSE: The purpose of this study was to investigate the effect of 5% terpenes (i.e., limonene, carvone, thymol, and cineole)/ethanol (EtOH) and iontophoresis on the in vitro permeability of luteinizing hormone releasing hormone (LHRH) through the porcine epidermis and biophysical changes in the stratum comeum (SC) lipids by fourier transform infrared (FT-IR) spectroscopy.
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19320284 Songkro S, Rades T, Becket G: Effects of some terpenes on the in vitro permeation of LHRH through newborn pig skin. Pharmazie. 2009 Feb;64(2):110-5.

The objective of this work was to investigate the effect of oxygen containing terpenes (carvacrol, menthol and carvone) at 5%w/v in hydroalcoholic mixtures (40% ethanol) on the permeation of LHRH across newborn pig skin in vitro.
12(0,0,1,7) Details