Protein Information

Name bone morphogenetic protein 2
Synonyms BMP 2; BMP 2A; BMP2; BMP2A; Bone morphogenetic protein 2 precursor; bone morphogenetic protein 2; Bone morphogenetic protein 2 precursors; bone morphogenetic protein 2s

Compound Information

Name sodium chlorate
CAS sodium chlorate

Reference List

PubMed Abstract RScore(About this table)
17020882 Jiao X, Billings PC, O'Connell MP, Kaplan FS, Shore EM, Glaser DL: Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 2007 Jan 12;282(2):1080-6. Epub 2006 Oct 3.

Depletion of cell surface HSPGs by heparinase III treatment or decreased glycosaminoglycan chain sulfation with sodium chlorate enhances BMP2 morpho-genetic bioactivity.
86(1,1,1,6) Details
16647687 Osses N, Gutierrez J, Lopez-Rovira T, Ventura F, Brandan E: Sulfation is required for bone morphogenetic protein 2-dependent Id1 induction. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1207-15. Epub 2006 May 2.

We have used sodium chlorate to inhibit sulfation in C2C12 cells and have analyzed BMP-2 induction of Id1.
1(0,0,0,1) Details