| Name | amphiregulin |
|---|---|
| Synonyms | AR; AREG; Amphiregulin; Amphiregulin precursor; Amphiregulin preproprotein; CRDGF; Colorectum cell derived growth factor; SDGF… |
| Name | sodium chlorate |
|---|---|
| CAS | sodium chlorate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9542658 | Nylander N, Smith LT, Underwood RA, Piepkorn M: Topography of amphiregulin expression in cultured human keratinocytes: colocalization with the epidermal growth factor receptor and CD44. In Vitro Cell Dev Biol Anim. 1998 Feb;34(2):182-8. Metabolic blockade of proteoglycan sulfation with sodium chlorate inhibited growth of the cells and concurrently enhanced the nuclear, but decreased the outer leading edge, labeling for amphiregulin. |
89(1,1,1,9) | Details |
| 8138579 | Piepkorn M, Lo C, Plowman G: Amphiregulin-dependent proliferation of cultured human keratinocytes: autocrine growth, the effects of exogenous recombinant cytokine, and apparent requirement for -like glycosaminoglycans. J Cell Physiol. 1994 Apr;159(1):114-20. Sodium chlorate, which blocks glycosaminoglycan sulfation, reversibly inhibited epidermal growth factor-dependent proliferation by 42%, exogenous amphiregulin-dependent proliferation by 75%, and autocrine growth by 95%; concurrent incubation with 1-100 micrograms/ml partially reversed this inhibition. |
41(0,1,1,11) | Details |
| 9828107 | Zvibel I, Brill S, Halpern Z, Papa M: Hepatocyte extracellular matrix modulates expression of growth factors and growth factor receptors in human colon cancer cells. Exp Cell Res. 1998 Nov 25;245(1):123-31. ECM from hepatocytes grown in the presence of nitrophenyl-beta-D-xylopyrannoside or sodium chlorate, which prevent formation of proteoglycan, as well as ECM treated with heparinase, had no effect on erb-B2 expression. Screening of autocrine growth factors and receptors showed that the cells expressed growth factors and receptors of the EGF family: EGF receptor, erb-B2, amphiregulin, and cripto. |
1(0,0,0,1) | Details |