Protein Information

Name ICA69
Synonyms 69 kDa islet cell autoantigen; ICA 1; ICA1; ICA69; ICAp69; Islet cell autoantigen 1; Islet cell autoantigen P69; islet cell autoantigen 1 (69kD)…

Compound Information

Name aldicarb
CAS

Reference List

PubMed Abstract RScore(About this table)
11029035 Pilon M, Peng XR, Spence AM, Plasterk RH, Dosch HM: The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion. Mol Biol Cell. 2000 Oct;11(10):3277-88.

A deletion mutant was isolated and found to exhibit resistance to the drug aldicarb (an inhibitor of acetylcholinesterase), suggesting defective neurotransmitter secretion in the mutant.
8(0,0,0,8) Details