| Name | P17 |
|---|---|
| Synonyms | Arsenic transactivated protein; AsTP; CHARAC17; CHRAC 17; CHRAC17; Chromatin accessibility complex 17; DNA polymerase II subunit 3; DNA polymerase epsilon subunit 3… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9539222 | Elster L, Banke T, Kristiansen U, Schousboe A, Wahl P: Functional properties of glycine receptors expressed in primary cultures of mouse cerebellar granule cells. Neuroscience. 1998 May;84(2):519-28. Scatchard analysis of the binding data obtained from P17 cerebellum showed a single population of binding sites (K (D) approximately 6 nM) and [3H] strychnine binding to membranes prepared from cultured neurons and P17 cerebellum was found to have the same sensitivity to the glycinergic agonists and |
81(1,1,1,1) | Details |
| 18234240 | Pedroarena CM, Kamphausen S: Glycinergic synaptic currents in the deep cerebellar nuclei. . Neuropharmacology. 2008 Apr;54(5):784-95. Epub 2007 Dec 23. Here, using whole cell recordings in rat cerebellar slices we demonstrated that after postnatal day 17 (> P17) glycinergic IPSCs can be readily evoked in large deep cerebellar nuclear neurons (DCNs), in the same way as in neonatal DCNs (P7-P10). Spontaneous glycinergic IPSCs were very rare but direct presynaptic depolarization by superfusion with elevated concentration or application of 4-aminopyridine consistently evoked strychnine sensitive IPSCs. |
2(0,0,0,2) | Details |
| 12154171 | Mangin JM, Guyon A, Eugene D, Paupardin-Tritsch D, Legendre P: Functional glycine receptor maturation in the absence of glycinergic input in dopaminergic neurones of the rat substantia nigra. J Physiol. 2002 Aug 1;542(Pt 3):685-97. A drastic but transient decrease in the responsiveness of DA neurones occurred around P17 concomitant to the functional switch from the homomeric state to the heteromeric state. The application of 1 microM gabazine blocked spontaneous or evoked inhibitory synaptic current, while the addition of 1 microM strychnine had no effect, suggesting a lack of functional glycinergic synapses on DA neurones. |
1(0,0,0,1) | Details |