| Name | CALU |
|---|---|
| Synonyms | CALU; Calumenin; Calumenin precursor; Crocalbin; IEF SSP 9302; Calumenins; Calumenin precursors; Crocalbins |
| Name | warfarin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20128861 | Lubitz SA, Scott SA, Rothlauf EB, Agarwal A, Peter I, Doheny D, van der Zee S, Jaremko M, Yoo C, Desnick RJ, Halperin JL: Comparative performance of gene-based warfarin dosing algorithms in a multiethnic population. J Thromb Haemost. 2010 Feb 2. Additional covariates tested with each model included race, concurrent medications, medications known to interact with warfarin, and previously described CYP4F2, CALU, and GGCX variants. |
31(0,1,1,1) | Details |
| 20200517 | Voora D, Koboldt DC, King CR, Lenzini PA, Eby CS, Porche-Sorbet R, Deych E, Crankshaw M, Milligan PE, McLeod HL, Patel SR, Cavallari LH, Ridker PM, Grice GR, Miller RD, Gage BF: A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans. Clin Pharmacol Ther. 2010 Apr;87(4):445-51. Epub 2010 Mar 3. |
19(0,0,3,4) | Details |
| 19958090 | Lee MT, Chen CH, Chou CH, Lu LS, Chuang HP, Chen YT, Saleem AN, Wen MS, Chen JJ, Wu JY, Chen YT: Genetic determinants of warfarin dosing in the Han-Chinese population. Pharmacogenomics. 2009 Dec;10(12):1905-13. MATERIALS & METHODS: In this study, we screened for SNPs in 13 genes (VKORC1, CYP2C9, CYP2C18, PROC, APOE, EPHX1, CALU, GGCX, ORM1, ORM2, factor VII and CYP4F2) and tested their associations with warfarin dosing with univariate and multiple regression analysis. |
6(0,0,1,1) | Details |
| 20020283 | Cadamuro J, Dieplinger B, Felder T, Kedenko I, Mueller T, Haltmayer M, Patsch W, Oberkofler H: Genetic determinants of acenocoumarol and phenprocoumon maintenance dose requirements. Eur J Clin Pharmacol. 2010 Mar;66(3):253-60. Epub 2009 Dec 18. OBJECTIVE: The variability in warfarin dose requirement is attributable to genetic and environmental factors. METHODS: Common single nucleotide polymorphisms (SNPs) in the genes encoding cytochrome P450 family member 2C9 (CYP2C9), vitamin K epoxide reductase complex subunit 1 (VKORC1), gamma-glutamyl carboxylase (GGCX), calumenin (CALU) and apolipoprotein E (APOE) were studied in 206 patients receiving AC or PC. |
2(0,0,0,2) | Details |
| 18374197 | Wallin R, Wajih N, Hutson SM: VKORC1: a warfarin-sensitive enzyme in metabolism and biosynthesis of -dependent blood coagulation factors. Vitam Horm. 2008;78:227-46. The first described inhibitor of the gamma-carboxylation system has been identified as calumenin, a resident chaperone in the endoplasmic reticulum (ER). |
1(0,0,0,1) | Details |